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Clinical Trials/NCT03432117
NCT03432117
Completed
Not Applicable

Multicenter Prospective Clinical Trial to Evaluate Efficacy of Respiratory Rehabilitation Personalized Mobile Services for Respiratory Diseases

Asan Medical Center5 sites in 1 country179 target enrollmentMay 15, 2017

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Respiratory Disease
Sponsor
Asan Medical Center
Enrollment
179
Locations
5
Primary Endpoint
change from baseline in real distance walked for 6 minutes
Status
Completed
Last Updated
8 years ago

Overview

Brief Summary

This trial is multicenter prospective study to evaluate clinical efficacy of respiratory rehabilitation personalized mobile services for respiratory disease.

Detailed Description

Patients with Lung Cancer or COPD who need respiratory rehabilitation were enrolled in this trial. The subjets were randomized to 3 group(A: Fixed respiratory rehabilitation program group, B: Mixed respiratory rehabilitation program group(Fixed respiratory rehabilitation for 6 weeks, and then responsive respiratory rehabilitation for 6 weeks) and C: Control group(Ordinary rehabilitation service of the site)). Patients in Group A\&B were provided with mobile application and wearable O2 saturation machine and mobile application monitors physical activity and provides 1. how to do stretching, weight training with The-ra Band 2. daily and weekly target of exercise 3. alarm algorithms depending on patient's respiratory status(purse rate and O2 saturation)

Registry
clinicaltrials.gov
Start Date
May 15, 2017
End Date
January 6, 2018
Last Updated
8 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Chang-Min Choi

associate professor

Asan Medical Center

Eligibility Criteria

Inclusion Criteria

  • Patients with Lung cancer or COPD
  • Patients with FEV1\<80% or FVC\<80% in Pulmonary function test
  • In case of COPD, post-bronchodilator FEV1 or FVC will be used.
  • Exceptionally Lung Cancer patients with operation, FEV1\>80% or FVC\>80% will be permitted
  • The distance walked for 6 minutes in 6-minute walk test ≥ 150 m
  • Patients with android phone
  • Patients who voluntarily agree to study participation and provide written informed consent form

Exclusion Criteria

  • Patients with diseases which could be cause of death or significant disability for 1 year after study enrollment.
  • Patients with diseases that are difficult to walk or improve walking at screening
  • Patients with significant diseases which are difficult to include in this study in accordance with the investigator's judgment
  • Patients who are illiterate or have communication limitations
  • Patients who have a difficulty to complete a questionnaire or are uncooperative due to deterioration of recognition function

Outcomes

Primary Outcomes

change from baseline in real distance walked for 6 minutes

Time Frame: 12 weeks

change from baseline in Modified Medical Research Council dyspnea score

Time Frame: 12 weeks

The MMRC dyspnea scale is a five-option grading system. The scale measures a person's limitation base on a scale of 0-4 and uses the final value to determine how much disability is caused by shortness of breath.

change from baseline in COPD Assessment Test(CAT) score

Time Frame: 12 weeks

The CAT is a validated, short and simple subject completed questionnaire which has been developed for use in routine clinical practice to measure the health status of subjects with COPD. Subjects are scored on eight items (cough, phlegm, chest tightness, breathlessness, activity limitation, confidence, sleep and energy) on a scale of 0-5 depending on their impact. The sum of scores for each item gives the subject's impact score ranging from 0 (no impact) to 40 (worst possible impact).

Secondary Outcomes

  • change from baseline in Physical activity(12 weeks)
  • subject satisfaction with health status(12 weeks)
  • subject satisfaction with service(12 weeks)
  • change in Healthcare resource utilisation(the number of hospitalization) in COPD(chronic obstructive pulmonary disease) Patients(12 weeks)
  • change in Healthcare resource utilisation(hospitalization period) in COPD(chronic obstructive pulmonary disease) Patients(12 weeks)
  • change in Healthcare resource utilisation(the number of visiting emergency room) in COPD(chronic obstructive pulmonary disease) Patients(12 weeks)

Study Sites (5)

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