Comparison of Post Operative Analgesic Efficacy of Quadratus Lumborum Block With Bupivacaine of Same Dose and Different Concentrations in Paediatric Patients Undergoing Unilateral Open Inguinal Hernia Repair
Overview
- Phase
- Phase 2
- Status
- Not yet recruiting
- Sponsor
- VMMC and Safdarjung Hospital
- Enrollment
- 76
- Locations
- 1
- Primary Endpoint
- To compare post operative analgesic efficacy of Quadratus lumborum block with bupivacaine
Overview
Brief Summary
This study is a prospective, interventional trial designed to assess the effectiveness of ultrasound-guided Quadratus Lumborum Block (QLB) for postoperative pain relief in children aged 1 to 7 years undergoing unilateral open inguinal hernia surgery. The research compares two groups receiving the same total dose of bupivacaine (0.75 mg/kg) but at different concentrations and volumes: Group A receives 0.3 ml/kg of 0.25% bupivacaine, while Group B receives 0.6 ml/kg of 0.125% bupivacaine. The primary outcome is pain score measured using the CHEOPS scale at 6 hours post-surgery. Secondary outcomes include pain scores at additional time intervals, time to first rescue analgesia, total analgesic consumption over 24 hours, and intraoperative fentanyl usage. The goal is to determine whether a lower concentration with higher volume offers pain relief comparable to a higher concentration with lower volume, while remaining within safe limits for pediatric patients.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Masking
- None
Eligibility Criteria
- Ages
- 1.00 Year(s) to 7.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Patients aged 1 – 7 years with American Society of Anesthesiologists physical status I-II scheduled for unilateral open inguinal hernia surgery.
Exclusion Criteria
- •EXCLUSION CRITERIA
- •Infection at the site of block
- •Coagulopathy
- •Pre-existing neurological disease
- •Allergy to local anesthetics.
Outcomes
Primary Outcomes
To compare post operative analgesic efficacy of Quadratus lumborum block with bupivacaine
Time Frame: CHEOPS score at 6 hours.
of same dose and different concentrations in paediatric patients undergoing open inguinal
Time Frame: CHEOPS score at 6 hours.
hernia repair using the CHEOPS score at 6 hours.
Time Frame: CHEOPS score at 6 hours.
Secondary Outcomes
- 1.To compare CHEOPS score at 0,3,8,18 and 24 hours.(2.To compare time to first rescue analgesia)
Investigators
Dr Mayank Singh
VMMC and Safdarjung Hopital