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ACUVUE® OASYS With Transitions™ Light Intelligent Technology™ Clinical Performance Registry

Completed
Conditions
Vision Satisfaction in Bright Light
Interventions
Device: ACUVUE® OASYS with Transitions™
Device: Silicone Hydrogel Contact Lens
Registration Number
NCT04116736
Lead Sponsor
Johnson & Johnson Vision Care, Inc.
Brief Summary

This registry study is a one-year, one-visit, observational, prospective, open-label, two-arm, multi-center, multi-national, post-market study of approximately 300 patients who have recently been fitted with the ACUVUE® OASYS with Transitions™ and approximately 300 patients who have recently been fitted with spherical nonphotochromic reusable marketed silicone hydrogel contact lenses (of any brand). Eligible subjects will be asked to complete a Patient Registration Questionnaire several times throughout the year.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
146
Inclusion Criteria
  • Potential subjects must satisfy all of the following criteria to be enrolled in the study:
  • Contact lens neophytes or those who have recently (i.e. within last 2 months) begun the use of a new lens type and have purchased a supply of lenses.
  • A minimum age of 18 years, with no maximum age.
  • The registrant must read and sign the Informed Consent form.
  • The registrant must appear able and willing to adhere to the instructions set forth in this clinical protocol.
Exclusion Criteria
  • Potential subjects who meet any of the following criteria will be excluded from participating in the study:
  • Current participant in another research study.
  • Employee or relative of site, or family member of Recruiting Practitioner or Johnson & Johnson.
  • Non-spherical contact lens wearers, i.e. toric or multifocal lenses.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
TEST LensACUVUE® OASYS with Transitions™Eligible subjects that are at least 18 years old, who have been recently fitted (within the last 2 months) with the ACUVUE® OASYS with Transitions™ will be asked to complete follow-up assessments performed online at approximately 2-weeks, 4-months, and 12-months following Visit 1.
CONTROL LensSilicone Hydrogel Contact LensEligible subjects that are at least 18 years old, who have been recently fitted (within the last 2 months) with spherical non-photochromic reusable marketed silicone hydrogel contact lenses (of any brand) will be asked to complete follow-up assessments performed online at approximately 2-weeks, 4-months, and 12-months following Visit 1.
Primary Outcome Measures
NameTimeMethod
Vision Satisfaction in Bright Lighting - 2-Week Questionnaire2-week questionnaire follow-up

Subjects will be asked to evaluate their vision satisfaction in bright lighting by rating their level of agreement with the statement "I am satisfied with the quality of my vision in bright lighting with these contact lenses" using a 5-point agreement Likert scale (Strongly Disagree, Disagree, Neither Agree Nor Disagree, Agree, and Strongly Agree). In the Control group 4 subjects were identified as ineligible after the screening visit because they were wearing ineligible Control lenses. Therefore, only 54 subjects were included in the Control group for the primary endpoint data summary. The number of missing responses in each lens group was reported.

Vision Satisfaction in Bright Lighting - 4-Month Questionnaire4-month questionnaire follow-up

Subjects will be asked to evaluate their vision satisfaction in bright lighting by rating their level of agreement with the statement "I am satisfied with the quality of my vision in bright lighting with these contact lenses" using a 5-point agreement Likert scale (Strongly Disagree, Disagree, Neither Agree Nor Disagree, Agree, and Strongly Agree). In the Control group 4 subjects were identified as ineligible after the screening visit because they were wearing ineligible Control lenses. Therefore, only 54 subjects were included in the Control group for the primary endpoint data summary. The number of missing responses in each lens group was reported.

Vision Satisfaction in Bright Lighting - 12-Month Questionnaire12-month questionnaire follow-up

Subjects will be asked to evaluate their vision satisfaction in bright lighting by rating their level of agreement with the statement "I am satisfied with the quality of my vision in bright lighting with these contact lenses" using a 5-point agreement Likert scale (Strongly Disagree, Disagree, Neither Agree Nor Disagree, Agree, and Strongly Agree). In the Control group 4 subjects were identified as ineligible after the screening visit because they were wearing ineligible Control lenses. Therefore, only 54 subjects were included in the Control group for the primary endpoint data summary.

Secondary Outcome Measures
NameTimeMethod
Serious or Significant Adverse EventsThroughout the duration of the study, up to 12 months

A serious adverse event is any untoward medical occurrence that is potentially sight-threatening, requires hospitalization, results in persistent or significant disability / incapacity, or requires intervention to prevent permanent damage.

Significant adverse events are usually symptomatic and warrant discontinuation (temporary or permanent) of the test article (excluding serious adverse events).

Overall Quality of Vision - 2-Week Questionnaire2-week questionnaire follow-up

Overall quality of vision was assessed subjectively using the item "I am satisfied with the overall quality of my vision with these contact lenses". The item used a 5-point agreement scale: Strongly Disagree, Disagree, Neither Agree Nor Disagree, Agree, and Strongly Agree. In the Control group 4 subjects were identified as ineligible after the screening visit because they were wearing ineligible Control lenses. Therefore, only 54 subjects were included in the Control group for this secondary endpoint data summary. The number of missing responses in each lens group was reported.

Overall Quality of Vision - 4-Month Questionnaire4-month questionnaire follow-up

Overall quality of vision was assessed subjectively using the item "I am satisfied with the overall quality of my vision with these contact lenses". The item used a 5-point agreement scale: Strongly Disagree, Disagree, Neither Agree Nor Disagree, Agree, and Strongly Agree. In the Control group 4 subjects were identified as ineligible after the screening visit because they were wearing ineligible Control lenses. Therefore, only 54 subjects were included in the Control group for this secondary endpoint data summary. The number of missing responses in each lens group was reported.

Overall Quality of Vision - 12-Month Questionnaire12-month questionnaire follow-up

Overall quality of vision was assessed subjectively using the item "I am satisfied with the overall quality of my vision with these contact lenses". The item used a 5-point agreement scale: Strongly Disagree, Disagree, Neither Agree Nor Disagree, Agree, and Strongly Agree. In the Control group 4 subjects were identified as ineligible after the screening visit because they were wearing ineligible Control lenses. Therefore, only 54 subjects were included in the Control group for this secondary endpoint data summary. The number of missing responses in each lens group was reported.

Overall Comfort - 2-Week Questionnaire2-week questionnaire follow-up

Overall comfort was assessed using the item "How would you rate the overall comfort of these contact lenses?". The item used the 5-point excellence scale, Excellent, Very Good, Good, Fair, and Poor. In the Control group 4 subjects were identified as ineligible after the screening visit because they were wearing ineligible Control lenses. Therefore, only 54 subjects were included in the Control group for this secondary endpoint data summary. The number of missing responses in each lens group was reported.

Overall Comfort - 4-Month Questionnaire4-month questionnaire follow-up

Overall comfort was assessed using the item "How would you rate the overall comfort of these contact lenses?". The item used the 5-point excellence scale, Excellent, Very Good, Good, Fair, and Poor. In the Control group 4 subjects were identified as ineligible after the screening visit because they were wearing ineligible Control lenses. Therefore, only 54 subjects were included in the Control group for this secondary endpoint data summary. The number of missing responses in each lens group was reported.

Overall Comfort - 12-Month Questionnaire12-month questionnaire follow-up

Overall comfort was assessed using the item "How would you rate the overall comfort of these contact lenses?". The item used the 5-point excellence scale, Excellent, Very Good, Good, Fair, and Poor. In the Control group 4 subjects were identified as ineligible after the screening visit because they were wearing ineligible Control lenses. Therefore, only 54 subjects were included in the Control group for this secondary endpoint data summary. The number of missing responses in each lens group was reported.

Pulfrich Effect2-week, 4-month, and 12-month questionnaire follow-up

Pulfrich effect was assessed subjectively using the item "While wearing these lenses, my depth perception of moving objects has NOT been impacted". Subjects who disagreed or strongly disagreed with the statement were considered to have experienced the Pulfrich effect. In the Control group 4 subjects were identified as ineligible after the screening visit because they were wearing ineligible Control lenses. Therefore, only 54 subjects were included in the Control group for this secondary endpoint data summary.

Trial Locations

Locations (20)

Optica Ronda

🇪🇸

Almeria, Spain

Natural Optics Balaguer

🇪🇸

Balaguer, Spain

Sanchez Rubal Ltd. - Sanchez Bregua

🇪🇸

La Coruna, Spain

Sanchez Rubal Ltd - Finisterre

🇪🇸

La Coruna, Spain

Centro Optico Raga

🇪🇸

Linares, Spain

Centro Optico Montero

🇪🇸

Madrid, Spain

Centro Boston de Optometria

🇪🇸

Madrid, Spain

Cirugia Ocular de Madrid

🇪🇸

Madrid, Spain

Opticalia Real Villa

🇪🇸

Madrid, Spain

Opticas ClaraVision

🇪🇸

Ontinyent, Spain

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Optica Ronda
🇪🇸Almeria, Spain
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