A study to evaluate the effects of platelet-rich plasma on hair regrowth in alopecia areata
Not Applicable
- Conditions
- Health Condition 1: null- Alopecia areata
- Registration Number
- CTRI/2017/02/007932
- Lead Sponsor
- All India Institute of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 30
Inclusion Criteria
Adult (age > 18 years) patients with alopecia areata of the scalp of duration atleast 6 months with symmetrically distributed patches of hair loss on the scalp
Exclusion Criteria
1.Patients with alopecia areata with asymmetrically distributed patches of hair loss on scalp
2.Patients with a co-existent scalp or hair disorder
3.Patients with thrombocytopenia ( <1 lac/mm3) on baseline haematological evaluation
4.Patients with underlying systemic illness, including autoimmune disorders
5.Pregnant or lactating female patients
6.Patients not consenting to participate in the study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.Severity of alopecia tool score at visits 1, 2, 3 and 4 <br/ ><br> <br/ ><br>2.Percentage of dystrophic hair on dermoscopic photomicrograph at visits 1, 2, 3 and 4 <br/ ><br> <br/ ><br>3.Patient global assessment at visits 2, 3 and 4 <br/ ><br> <br/ ><br>4.mRNA expression profile of Th1, Th2, Th17 and T-regulatory cell specific-markers in the lesional skin at visits 1 and 4 <br/ ><br> <br/ ><br>Timepoint: Visits 1, 2, 3 and 4. Every visit is at one monthly interval.
- Secondary Outcome Measures
Name Time Method Quantitative levels of Th1, Th2, Th17 and T-regulatory cell specific-markers in the lesional skin by immunohistochemistry at visits 1 and 4Timepoint: Visits 1 and 4