The Effect of External Diaphragmatic Pacemaker on the Patients With Chronic Cor Pulmonale
Not Applicable
Completed
- Conditions
- Chronic Cor Pulmonale
- Interventions
- Device: external diaphragmatic pacemaker group
- Registration Number
- NCT02976324
- Lead Sponsor
- Zhang Xiangyu
- Brief Summary
This study evaluates the effect of external diaphragmatic pacemaker on the patients with chronic cor pulmonale. Half of participants will receive external diaphragmatic pacemaker, while the other half will receive routine therapy.
- Detailed Description
Investigate the effect of external diaphragmatic pacemaker on chronic cor pulmonale, the indicators include: respiratory muscle force, diaphragmatic degree of excursion and thickness, pulmonary artery pressure, respiratory distress, feeling of fatigue and quality of life, pulmonary function,NT-proBNP,PaO2 and PaCO2.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
- diagnosis of chronic cor pulmonale and admit to hospital
Exclusion Criteria
- pneumothorax or mediastinal emphysema
- active tuberculosis
- install a cardiac pacemaker
- acute cardiocerebrovascular events: acute myocardial infarction, acute myocarditis, severe arrhythmia, severe cerebrovascular accidents.
- pregnancies
- end-stage patients (expected survival time less than 6 months)
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description external diaphragmatic pacemaker group external diaphragmatic pacemaker group use the external diaphragmatic pacemakerI 9 counts per minute, with stimulate frequency 40 Hz
- Primary Outcome Measures
Name Time Method cardiopulmonary function 10 days six miunte walk test
- Secondary Outcome Measures
Name Time Method MIP 10 DAYS MAX INSPIRATORY PRESSURE
Trial Locations
- Locations (1)
Shanghai Tenth People's Hospital
🇨🇳Shanghai, Shanghai, China