Effect of a Novel Blend of Plant Protein and Additional Ingredients on Resistance Training Adaptations

Not Applicable

Completed

• Conditions: Resistance Exercise

• Registration Number: NCT06908811
• Lead Sponsor: Lindenwood University

Brief Summary

This study seeks to compare the observed changes in resistance training adaptations (strength, performance, body composition, recovery, and lactate responses) after supplementation of isocaloric and isonitrogenous amounts of a novel plant protein formulation against changes observed in a pea/rice plant protein blend, whey protein, and a carbohydrate placebo in healthy resistance-trained men and women between the ages of 18-39.

Detailed Description

This study seeks to compare the observed changes in resistance training adaptations (strength, performance, body composition, recovery, and lactate responses) after supplementation of isocaloric and isonitrogenous amounts of a novel plant protein formulation against changes observed in a pea/rice plant protein blend, whey protein, and a carbohydrate placebo in healthy resistance-trained men and women between the ages of 18-39.

Study Timeline

• Study Start: 2022-08-19
• Primary Completion: 2025-01-17
• Study Completion: 2025-01-17
• Status Verified: 2025-03
• Study First Submitted: 2025-03-27
• Study First Submitted QC: 2025-03-27
• Last Update Submitted: 2025-03-27
• Study First Posted: 2025-04-03
• Last Update Posted: 2025-04-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Change in 4-Compartment Lean Mass	Week 0, Week 4, and Week 8	Lean mass will be assessed using a 4-compartment model, which includes measurements of body density, total body water, and bone mineral content.
Change in Perceptual Indicators of Training State	Week 0, Week 4, and Week 8	Participants will rate their readiness to train, soreness, recovery, energy, and sleep quality using 100-mm visual analog scales. Each scale is anchored with contextually appropriate statements such as "Lowest Possible" and "Highest Possible."
Change in Profile of Mood States (POMS) Score	Week 0, Week 4, and Week 8	Mood state will be assessed using the Profile of Mood States (POMS) questionnaire, a validated tool for measuring transient affective states. The POMS consists of six subscales (Tension-Anxiety, Depression-Dejection, Anger-Hostility, Vigor-Activity, Fatigue-Inertia, and Confusion-Bewilderment), with a Total Mood Disturbance (TMD) score calculated by summing negative subscale scores and subtracting the Vigor score. Higher TMD scores indicate greater mood disturbance, while lower scores indicate improved mood state.
Change in Pressure to Pain Threshold	Week 0, Week 4, and Week 8	Pressure pain threshold will be assessed using a digital algometer to determine the minimum pressure required to elicit pain. Higher scores indicate higher tolerance to pain.
Change in Handgrip Strength	Week 0, Week 4, and Week 8	Maximal handgrip strength will be assessed using a calibrated hand dynamometer. Higher values indicate greater strength.
Change in Isometric Mid-Thigh Pull Force	Week 0, Week 4, and Week 8	Maximal force output will be assessed using an isometric mid-thigh pull on a force plate, measured in Newtons. Higher scores equal greater force production
Change in Hex Bar Deadlift One-Repetition Maximum (1RM)	Week 0, Week 4, and Week 8	Maximal hex bar deadlift strength will be assessed using a standardized one-repetition maximum (1RM) test.
Change in Bench Press One-Repetition Maximum (1RM	Week 0, Week 4, and Week 8	Maximal upper-body strength will be assessed using a standardized one-repetition maximum (1RM) bench press test.
Change in Isokinetic Peak Knee Extension Torque	Week 0, Week 4, and Week 8	Peak torque of the quadriceps will be assessed using an isokinetic dynamometer. Higher values indicate greater knee extensor strength.
Performance in 5 Sets of Hex Bar Deadlift Protocol	Week 0, Week 4, and Week 8	Strength endurance will be assessed using a hex bar deadlift protocol consisting of 3 sets of 10 repetitions at 70% 1RM and 2 sets to failure at 80% 1RM. Repetition count and total volume lifted will be recorded.

Secondary Outcome Measures

Name	Time	Method
Change in 4-Compartment Fat Mass	Week 0, Week 4, and Week 8	Fat mass will be measured using a 4-compartment model, which integrates body density, total body water, and bone mineral content.
Change in 4-Compartment Fat-Free Mass	Week 0, Week 4, and Week 8	Fat-free mass will be assessed using a 4-compartment model, providing a more precise measurement of body composition changes.
Change in 4-Compartment Percent Body Fat	Week 0, Week 4, and Week 8	Body fat percentage will be assessed using a 4-compartment model.
Change in Total, Extracellular, and Intracellular Body Water	Week 0, Week 4, and Week 8	Hydration status will be measured using bioelectrical impedance analysis (BIA) to assess total, extracellular, and intracellular body water content.
Change in Dry Fat-Free Mass	Week 0, Week 4, and Week 8	Dry fat-free mass will be assessed using a combination of dual-energy X-ray absorptiometry (DEXA) and bioelectrical impedance analysis (BIA) for a comprehensive measure of lean tissue mass.

Trial Locations

Locations (1)

Exercise and Performance Nutrition Laboratory; 🇺🇸 St. Charles, Missouri, United States