Pharmacogenetics of angiotensin converting enzyme and relationships with angiotensin converting enzyme activity in Thai populatio

Not Applicable

Completed

• Conditions: ACE inhibitor- induced cough; pharmacogenetics; angiotensin converting enzyme activity; ACE

• Registration Number: TCTR20180718001
• Lead Sponsor: Faculty of Medicine, Thammasat University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2018-07-18
• Study Completion: 2019-02-05
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Thai healthy volunteers

Exclusion Criteria

1. Drinking alcohol smoking drug abuse
2. Pregnancy lactation hormonal contraceptive use
3. Steroid and herbal medicines esp Centella asiatica use within 2 weeks before blood collection
4. Underlying diseases hypertension cardiovascular disease thyroid disease diabetes mellitus pulmonary disease cirrhosis leprosy AIDS cancer

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Angiotensin converting enzyme polymorphisms end of experiment Real-time PCR based alleic discrimination,Angiotensin converting enzyme polymorphisms end of experiment Real-time PCR based alleic discrimination

Secondary Outcome Measures

Name	Time	Method
Angiotensin converting enzyme activity end of experiment Spectrophotometer assays