Endoscopic Band Ligation for Treating Reflux Disease

Not Applicable

Not yet recruiting

• Conditions: GERD
• Interventions: Device: Band Ligation

• Registration Number: NCT06126055
• Lead Sponsor: El Katib Hospital

Brief Summary

GERD is a chronic disease the require different treatment modalities; non have proven long term efficacy with concerns about their safety. The use of band ligation in endoscopy appears safe, repeatable with short learning curve. Placing multiple bands at the Z-line can create a fibrous ring in the distal esophagus acting as a barrier against reflux of gastric content.

Detailed Description

The aim of the study is the complete resolution of reflux symptoms without the use of any drug.

Study Timeline

• Study First Submitted: 2023-11-03
• Study First Submitted QC: 2023-11-08
• Study First Posted: 2023-11-13
• Status Verified: 2024-08
• Last Update Submitted: 2024-08-26
• Last Update Posted: 2024-08-27
• Study Start: 2024-09-01
• Primary Completion: 2026-01-01
• Study Completion: 2026-01-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

• Symptomatic GERD

Exclusion Criteria

• Any previous surgery for GERD

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Off PPI	Band Ligation	No symptoms of reflux

Primary Outcome Measures

Name	Time	Method
Endoscopic Band Ligation for GERD	1 month	Resolution of reflux symptoms and stopping proton pump inhibitors.

Trial Locations

Locations (1)

Endoscopy Unit Cairo University; 🇪🇬 Cairo, Egypt