Effects of the breathing response during reduced oxygen tension and simultaneous infusion of dexmedetomidine compared to propofol, two sedating agents.
- Conditions
- Healthy volunteers and the acute hypoxic ventilatory response during sedation with dexmedetomidine compared to propofol.MedDRA version: 14.1Level: LLTClassification code 10068084Term: Anesthesia procedureSystem Organ Class: 100000004865MedDRA version: 14.1Level: LLTClassification code 10062825Term: Monitored anaesthesia care sedationSystem Organ Class: 100000004865Therapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03]
- Registration Number
- EUCTR2012-005812-24-SE
- Lead Sponsor
- Karolinska University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- Male
- Target Recruitment
- 21
Inclusion Criteria
Healthy male volunteers 18-40 years of age. No allergy or medication. Non-smokers, non-tobacco user. Normal weight, that is BMI<26.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 21
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range
Exclusion Criteria
Those who do not fulfill the inclusion criteria. Snoring during sleep. A beard or anatomy that unables the breathing mask to fit tightly.
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method