Evaluation of safety and oxidative stress effect of food supplement from Tiliacora triandra (Colebr.) Diels in overweight volunteers

Phase 1

Completed

• Conditions: Healthy conditions; overweight; high cholesterol; adult

• Registration Number: TCTR20190517005
• Lead Sponsor: Agricultural Research Development Agency (ARDA)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2019-04-07
• Study Start: 2019-05-17
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

- Live in Khon Kaen, Thailand
- Aged between 25-50 years old
- Body mass index more than 23
- Cholesterol more than 220 mg/dL
-All volunteers should not use other nutraceutical compounds or herbs or drugs
which influenced on the nervous system function and bone at least 3 months before participating in this study
- On the day of the study, all volunteers felt well and refrain from drinking tea or
coffee, or alcohol

Exclusion Criteria

• Cardiovascular disease
• Respiratory disease
• Neuropsychological disorders
• Diabetes
• Liver disease
• Renal disease
• Endocrine dysfunction
• Autoimmune disease

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
cholesterol 8 weeks clinical laboratory

Secondary Outcome Measures

Name	Time	Method
Malondialdehyde level (MDA), Superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase act 8 weeks Elisa methods,clinical chemistry 8 weeks clinical laboratory,Complete blood count 8 weeks clinical laboratory,Homeostasis Model Assessment Insulin Resistance (HOMA) index และ atherosclerosis index (AI) 8 weeks clinical laboratory,total phenolic compound 8 weeks Elisa methods