Long-term Clinical Outcome in Patients Undergoing Remote Ischemic Conditioning Before Primary Percutaneous Coronary Intervention for ST-elevation Myocardial Infarction: a Follow-up Study

University of Aarhus1 site in 1 country251 target enrollmentFebruary 2007

ConditionsST-elevation Myocardial Infarction (STEMI)

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: ST-elevation Myocardial Infarction (STEMI)
Sponsor: University of Aarhus
Enrollment: 251
Locations: 1
Primary Endpoint: Major adverse cardiac and cerebrovascular events (MACCE)
Last Updated: 11 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The aim of this prospective follow-up study is to investigate 5-year clinical outcome in patients with ST-elevation myocardial infarction undergoing remote ischemic conditioning before primary percutaneous coronary intervention.

Registry

clinicaltrials.gov

Start Date

February 2007

End Date

December 2015

Last Updated

11 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

University of Aarhus

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Chest pain before admission to hospital within 12 h of onset, ST-segment elevation of \> 0,1 mV in 2 or more contiguous leads, 18 years or older.

Exclusion Criteria

•left bundle branch block, previous myocardial infarction, fibrinolytic treatment in the previous 30 days, previous coronary bypass surgery, left main stem stenosis requiring coronary bypass surgery, severe heart failure requiring mechanical ventilation or use of an intra-aortic balloon pump.

Outcomes

Primary Outcomes

Major adverse cardiac and cerebrovascular events (MACCE)

Time Frame: 5 years

MACCE defined as all-cause mortality, readmission for heart failure, myocardial infarction, and ischemic stroke/transient ischemic attack. Data are collected from Danish nationwide registries and medical records.