Autonomic Responses During the Valsalva Maneuver and Deep Breathing Test Depend on the Experimental Setup

Not Applicable

Completed

• Conditions: Autonomic Nervous System Diseases
• Interventions: Other: Autonomic Function Testing

• Registration Number: NCT02397681
• Lead Sponsor: Danish Pain Research Center

Brief Summary

The purpose of this study is to determine the effects of procedural differences during the Valsalva maneuver and deep breathing test in autonomic nervous system testing.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-01
• Study First Submitted: 2015-02-11
• Study First Submitted QC: 2015-03-19
• Study First Posted: 2015-03-25
• Primary Completion: 2015-05
• Study Completion: 2015-08
• Status Verified: 2018-01
• Last Update Submitted: 2018-01-30
• Last Update Posted: 2018-01-31

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 40

Inclusion Criteria

• male
• ≥ 18 year
• normal ECG-12

Exclusion Criteria

• any known disease
• smoking
• any intake of regular medicine

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Experimental	Autonomic Function Testing	-

Primary Outcome Measures

Name	Time	Method
Blood pressure changes to cardiovascular adrenergic activation	3 hours
Heart rate changes to parasympathetic activation	3 hours

Secondary Outcome Measures

Name	Time	Method
Expiratory pressure during the Valsalva maneuver	3 hours
Expiratory duration during the Valsalva maneuver	3 hours
Air volume exchanged per respiratory cycle during deep respiration	3 hours

Trial Locations

Locations (1)

Danish Pain Research Center, Aarhus University Hospital; 🇩🇰 Aarhus, Denmark