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Clinical Trials/NCT01724905
NCT01724905
Completed
Not Applicable

Weight Loss and Maintenance for Individuals With Intellectual Developmental Disabilities (IDD)

Joseph Donnelly1 site in 1 country151 target enrollmentMay 2011
ConditionsWeight Loss

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Weight Loss
Sponsor
Joseph Donnelly
Enrollment
151
Locations
1
Primary Endpoint
Weight loss between experimental diet (SLDm) and recommended care diet (RC)
Status
Completed
Last Updated
10 years ago

Overview

Brief Summary

Individuals with intellectual developmental disabilities (IDD) have obesity rates that exceed those in the general population, consume energy dense diets, and perform very little physical activity (PA). Overweight and obesity are independent risk factors for chronic disease such as cancer, diabetes, hypertension, and cardiovascular disease in both the general population and those with IDD.

The investigators modified the Stop Light Diet (SLDm) to include reduced energy pre-packaged meals (PM) for 6 months, encouraged consumption of low energy shakes and 35 fruits and vegetables (F/V) per week. The investigators will compare participants who use the SLDm with participants who use a reduced energy and fat diet with meal plans, based off of the current American Dietetic Association recommended car for weight reduction plan.

Registry
clinicaltrials.gov
Start Date
May 2011
End Date
July 2015
Last Updated
10 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Joseph Donnelly
Responsible Party
Sponsor Investigator
Principal Investigator

Joseph Donnelly

Professor

University of Kansas Medical Center

Eligibility Criteria

Inclusion Criteria

  • Diagnosis of mile to moderate IDD as determined by a Community Service Provider operating in Kansas under the auspices of a Community Developmental Disability Organization (CDDO)
  • Able to understand and give informed consent
  • If there is a guardian with power of attorney, both the guardian and participant must give informed consent
  • Participants must live in a supported living condition either at home or with no more than 1-4 residents and have a care giver (ie. parent, staff) who assists with food shopping, meal planning, and meal preparation
  • Overweight or obese determined by a BMI \> 25 kg/m2
  • Able to walk
  • Clearance provided from physician
  • Able to communicate preferences

Exclusion Criteria

  • Uncontrolled hypertension
  • Severe heart disease
  • Cancer diagnosis
  • Positive for HIV

Outcomes

Primary Outcomes

Weight loss between experimental diet (SLDm) and recommended care diet (RC)

Time Frame: Change from Baseline in Weight at 18 months

The experimental diet is the Stop Light Diet modified (SLDm) and includes PM, 35 F/V per week, and low energy shakes. The Investigators will compare this to the RC diet that uses traditional meal plans and includes 35 F/V per week. Weight to be measured following an overnight fast of approximately 12 hours. Weight will be measured in kg. Each person will be weighed in a hospital gown between 8 and 10 am, using a calibrated scale to the nearest 0.1kg.

Secondary Outcomes

  • Comparison of chronic disease factors - Blood Pressure(Change from Baseline in Blood Pressure at 18 months)
  • Comparison of chronic disease factors - Glucose(Change from Baseline in Glucose at 18 months)
  • Comparison of chronic disease factors - HDL(Change from Baseline in HDL-cholesterol Pressure at 18 months)
  • Comparison of chronic disease factors - LDL(Change from Baseline in LDL-cholesterol Pressure at 18 months)
  • Comparison of chronic disease factors - Insulin(Change from Baseline in Insulin Pressure at 18 months)

Study Sites (1)

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