跳至主要内容
临床试验/NCT01709617
NCT01709617Unknown不适用

Sucrose as a Preferred Carbohydrate in Sports Nutrition

Maastricht University Medical Center2 个研究点 分布在 1 个国家目标入组 17 人开始时间: 2012年11月最近更新:
适应症

试验速览

阶段
不适用
入组人数
17
试验地点
2
主要终点
Exogenous carbohydrate oxidation rate (Part A)

研究概览

简要总结

Carbohydrates are an integral component of sports nutrition. Providing carbohydrate (CHO) during exercise delays the onset of fatigue and improves exercise performance by maintaining high rates of CHO oxidation. Traditionally, glucose, or glucose polymers have been the preferential CHO source found in sports drinks. However, during the intestinal absorption of large amounts of glucose (>1.2 g/min), sodium-dependent glucose transporters (SGLT1) may become fully saturated, potentially limiting the rate of exogenous CHO oxidation. In an effort to evade this limitation, research has suggested using multiple transportable carbohydrates in the composition of sports drinks. Multiple transportable carbohydrates are combinations of simple sugars that use different intestinal transporters during the absorption process. Ingesting multiple transportable carbohydrates may enhance the capacity for total intestinal CHO absorption, leading to an increase in the rate of exogenous CHO oxidation. Our purpose will be to examine the disaccharide sucrose in it's ability to provide exogenous fuel during and following prolonged exercise.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
盲法
Double (Participant, Investigator)

入排标准

年龄范围
18 Years 至 40 Years(Adult)
性别
Male
接受健康志愿者

入选标准

  • 18 - 40 years of age
  • Endurance trained cyclist/triathlete
  • VO2 max ≥ 50 ml/kg/min
  • BMI < 25 kg/m2

排除标准

  • Use of medication

结局指标

主要结局

Exogenous carbohydrate oxidation rate (Part A)

时间窗: 180 min during trials 1-3

Carbohydrate oxidation as measured by breath samples

Endogenous carbohydrate oxidation (Part A)

时间窗: 180 min during trials 1-3

endogenous carbohydrate oxidation as measured through breath samples during trials 1-3

Glycogen utilization (Part B)

时间窗: 6 h post exercise during trials 4-6

Glycogen utilization measured through a muscle biopsy sample at post (\~90 min), 3 and 6 h post exercise. Part B; trials 4-6.

次要结局

  • Indirect calorimetry (Part A)(every 30 min up to 180 min during trials 1-3)
  • Plasma glucose(every 30 min up to 180 min during trials 1-6)
  • Plasma insulin(every 30 minutes up to 180 min during trials 1-6)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

Loading locations...

相似试验