The acute effects of whey protein isolate on metabolic syndrome risk factors in overweight and obese individuals

Not Applicable

Completed

• Conditions: Metabolic syndrome risk factors in overweight or obese individuals; Diet and Nutrition - Obesity

• Registration Number: ACTRN12609000178246
• Lead Sponsor: Dairy Australia

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2009-04-17
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 20

Inclusion Criteria

Post-menopausal
Non-smoker
Body mass Index (BMI) between 25-35 kg/m2
Not taking regular medication
Not taking supplements, vitamins or herbal remedies
Weight stable
Less than 1-2 serves dairy per day
No major diseases/illness

Exclusion Criteria

Smokers
Regular medications, especially those affecting blood lipids, blood pressure or thyroid
Premenopausal or perimenopausal
On a weight loss regime

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Improved blood lipid and lipoprotein status as well as improved glucose and insulin sensitivity after the ingestion of the whey protein isolate[Fasting blood samples taken before liquid preload and then taken post meal (in minutes) - +15, 30, 60, 90, 120, 180, 240, 360.];Improved blood pressure after ingestion of the whey protein isolate.Systolic blood pressure (SBP), diastolic blood pressure (DBP) and resting heart rate were measured on the left arm of participants with an automated sphygmomanometer (Dinamap ProCare). Subjects rested in a supine position before and during measurements.[Blood pressure taken before test meal & liquid preload, and then taken post meal (in minutes) - +30, 60, 90, 120, 180, 240, 360.];Improved vascular endothelial function via Sphygmocor pulse wave analysis (PWA) after the ingestion of the whey protein isolate[PWA readings before test meal & liquid preload, then post meal (in minutes) - 30, 60, 90, 120, 180, 240, 360.]

Secondary Outcome Measures

Name	Time	Method
Greater satiety after ingesting the whey protein isolate relative to control.[Visual analogue scale (VAS) completed by subjects before test meal & liquid preload, and then post meal (in minutes) - 30, 60, 90, 120, 180, 240, 360.]