The chronic effects of whey protein isolate on metabolic syndrome risk factors in overweight and obese individuals

Not Applicable

Completed

• Conditions: Metabolic risk factors in overweight and obese individuals; Diet and Nutrition - Obesity

• Registration Number: ACTRN12609000175279
• Lead Sponsor: Dairy Australia

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2009-04-16
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

Body Mass Index (BMI) between 25-35kg/m2
Not on regular medications
Non-smoker
Have low dairy intake (<1-2 serves/day)
Less than 1 alcoholic drink/day for women, 2 for men
Weight stable
No major diseases or disorders

Exclusion Criteria

Smokers
On regular medications, especially those affecting blood pressure, thryoid, blood lipids
High consumption of dairy or alcohol
Taking regular supplements, vitamins, herbal remedies
On a weight loss regime

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Improved blood lipid, lipoprotein profile, glucose tolerance and insulin response[Blood samples taken a 0, 6 and 12 weeks];Improved blood pressure after 12 weeks. Blood pressure will be measured by research assistant using a Systolic blood pressure (SBP), diastolic blood pressure (DBP) measured on the left arm of participants with an automated sphygmomanometer (Dinamap ProCare). Subjects rested in a supine position before and during measurements.[Measured at 0, 6 and 12 weeks];Reduced body fat mass & preserved or increased muscle mass[Measured by Dual-energy X-ray Absorptiometry (DEXA) at 0 and 12 weeks plus<br>Weight and anthropometric measures taken at 0, 6 and 12 weeks]

Secondary Outcome Measures

Name	Time	Method
Improved vascular endothelium function via Sphygmocor pulse wave analysis (PWA)[PWA readings at 0, 6 and 12 weeks]