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临床试验/NCT02985606
NCT02985606已完成不适用

How Does Altering the Timing of Pre-exercise Low-dose Caffeine Ingestion Affect Endurance Exercise Performance

University of Exeter2 个研究点 分布在 1 个国家目标入组 14 人开始时间: 2016年11月最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
14
试验地点
2
主要终点
Work done in kilojoules (kJ) during a 15 minute time trial on a cycle ergometer

研究概览

简要总结

Investigate how manipulating the time between caffeine ingestion and exercise may alter exercise performance and cognition

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Basic Science
盲法
Triple (Participant, Investigator, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 40 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • vo2max > 55 ml/kg/min
  • females on contraceptive pill

排除标准

  • recent skeletal muscle injury
  • cardiovascular injury
  • metabolic disease

研究组 & 干预措施

Caffeine -60

Active Comparator

Caffeine at 60 minutes prior to time trial

干预措施: Caffeine powder -60 (Other)

Caffeine -60

Active Comparator

Caffeine at 60 minutes prior to time trial

干预措施: Placebo powder -30 (Other)

Caffeine -60

Active Comparator

Caffeine at 60 minutes prior to time trial

干预措施: Placebo powder 0 (Other)

Caffeine -30

Active Comparator

Caffeine at 30 minutes prior to time trial

干预措施: Placebo powder 0 (Other)

Caffeine -30

Active Comparator

Caffeine at 30 minutes prior to time trial

干预措施: Caffeine powder -30 (Other)

Caffeine -30

Active Comparator

Caffeine at 30 minutes prior to time trial

干预措施: Placebo powder -60 (Other)

Caffeine 0

Active Comparator

Caffeine immediately prior to time trial

干预措施: Caffeine powder 0 (Other)

Caffeine 0

Active Comparator

Caffeine immediately prior to time trial

干预措施: Placebo powder -60 (Other)

Caffeine 0

Active Comparator

Caffeine immediately prior to time trial

干预措施: Placebo powder -30 (Other)

Placebo

Placebo Comparator

Placebo drink at all time points

干预措施: Placebo powder -60 (Other)

Placebo

Placebo Comparator

Placebo drink at all time points

干预措施: Placebo powder -30 (Other)

Placebo

Placebo Comparator

Placebo drink at all time points

干预措施: Placebo powder 0 (Other)

结局指标

主要结局

Work done in kilojoules (kJ) during a 15 minute time trial on a cycle ergometer

时间窗: 15 minutes

次要结局

  • Collection of saliva for genotyping of CYP1A2(30 mintes)
  • Change in plasma caffeine concentration and metabolites(2 hours 45 minutes)
  • Change in cognitive function measured using stroop test(2 hours 45 minutes)
  • Whole body fuel substrate utilisation measured using indirect calorimetry(10 minutes)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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