Effect of Exercise Timing on Energy Intake and Appetite in Adolescents With Obesity: the TIMEX 3 Study

Not Applicable

• Conditions: Pediatric Obesity
• Interventions: Behavioral: CON; Behavioral: EX-30; Behavioral: EX-90

• Registration Number: NCT03968458
• Lead Sponsor: University Hospital, Clermont-Ferrand

Brief Summary

The aim of the present study is to compare the effect of the timing (30 vs. 90 minutes) between a fixed exercise and the following test meal on energy intake, appetite feelings and food reward in adolescents with obesity.

Detailed Description

The present study will compare the nutritional response to the realisation of an acute exercise 90 minutes or 30 minutes before an ad libitum buffet meal in adolescents with obesity. 18 adolescents with obesity will be asked to randomly complete three experimental sessions: i) one control session (rest); ii) one session with an acute exercise realized 90 minutes before lunch; iii) one session with the same exercise performed 30 minutes before lunch. Their ad libitum energy intake will be assessed during lunch as well as at dinner time. Appetite feelings will be assessed at regular intervals and their food reward in response to the lunch will also be assessed.

Study Timeline

• Study First Submitted: 2019-04-29
• Study First Submitted QC: 2019-05-27
• Study First Posted: 2019-05-30
• Study Start: 2019-08-31
• Status Verified: 2019-10
• Last Update Submitted: 2019-10-04
• Last Update Posted: 2019-10-07
• Primary Completion: 2020-06-30
• Study Completion: 2020-07-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 18

Inclusion Criteria

• BMI percentile > 97th percentile according to the french curves.
• ages 12-16 years old
• Signed consent form
• being registered in the national social security system
• no contraindication to physical activity

Exclusion Criteria

• Previous surgical interventions that is considered as non-compatible with the study.
• Diabetes
• weight loss during the last 6 months
• cardiovascular disease or risks

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Obese adolescents	CON	18 adolescents with obesity are involved and will perform the three conditions.
Obese adolescents	EX-30	18 adolescents with obesity are involved and will perform the three conditions.
Obese adolescents	EX-90	18 adolescents with obesity are involved and will perform the three conditions.

Primary Outcome Measures

Name	Time	Method
Change of energy intake measured during an ad libitum buffet meal (in kcal).	day 1 , day 8, day 15	Change of food intake will be measured ad libitum during a lunch buffet. The adolescents will be offered an ad libitum buffet-type meal composed based on their food intake preferences. Their intake will be weighted using an electronic food scale by a member of the investigation team and then analysed using Bilnuts software.

Secondary Outcome Measures

Name	Time	Method
Hunger feelings	day 1 , day 8, day 15	: hunger area under the curve will be assessed using visual analogue scale through a the day
Food reward	day 1 , day 8, day 15	The participants will be asked to complete a validated computer-based procedure to measure food reward (Leeds Food Preference Questionnaire; LFPQ)

Trial Locations

Locations (1)

CHU de Clermont-Ferrand; 🇫🇷 Clermont-Ferrand, France