To Compare effect of dexmedetomidine and fentanyl on Propofol dose requirement
Phase 3
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2023/10/058225
- Lead Sponsor
- Dr Fayaz Musthafa
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients of age group 18 to 55 years, undergoing elective surgeries under general anaesthesia.
- Patients classified under American Society of Anaesthesiologists (ASA) 1 and 2 after thorough Pre-Anaesthetic evaluation.
Exclusion Criteria
1.Patient refusal
2.Pregnant women
3.Patients with BMI of 30kg/m2 and more
4.Patients with history of epilepsy, and patients who are currently on anti-epileptic medication
5.Patients with anticipated difficult airway – Mallampatti Grade 3 or 4, short neck.
6.Patients with history of allergy to Propofol, Fentanyl or Dexmedetomidine
7.Patients undergoing emergency surgeries.
8.Patients with history of alcohol abuse, drug abuse.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The outcome is to determine the dose at which propofol causes loss of verbal contact, when administered after usage of fentanyl or dexmedetomidine.Timepoint: Monitoring is done at 1-minute interval, for 8 minutes, from the time of administration of fentanyl or dexmedetomidine, to the time of intubation.
- Secondary Outcome Measures
Name Time Method To assess hemodynamic stability. <br/ ><br>- to assess adverse effects, if any.Timepoint: To assess hemodynamic stability from the time of induction to the time of laryngoscopy and intubation.