to compare dexmedetomidine versus nitroglycerine as a hypotensive agent causing less blood loss in posterior fixation surgery of spine.
Phase 4
- Conditions
- Health Condition 1: null- age 18-65yrs ,ASA I and II
- Registration Number
- CTRI/2018/04/013065
- Lead Sponsor
- Vardhaman Mahavir Medical College And Safdarjung Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Patients of age 18-65yrs undergoing posterior fixation of spine surgery under general anaesthesia
2.ASA I and II
Exclusion Criteria
1.Patients with hypertension
2.Patients with history of significant systemic disorders ( like cardiovascular, respiratory , central nervous system, hepatic and renal )
3.Patients with bleeding disorders.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare intra-operative haemodynamic changes and blood loss with infusion of dexmedetomidine and nitroglycerine in patients undergoing posterior fixation surgery of spine.Timepoint: intra-operative
- Secondary Outcome Measures
Name Time Method To compare the recovery characteristics and side effects of both these drugs in patients undergoing posterior fixation surgery of spine.Timepoint: intra-operative