COMPARISION OF EFFECTIVENESS OF DEXMEDETOMIDINE(A MULTIPURPOSE DRUG USED IN ANAESTHESIA) VS ESMOLOL(USED FOR CONTROL OF HIGH BP & HEART RATE) IN DECREASING THE HYPERTENSION & TACHYCARDIA OCCURING DURING PASSAGE OF BREATHING TUBE INTO LUNGS IN PATIENTS WITH HIGH BP WHO ARE ON TREATMENT
- Conditions
- Health Condition 1: null- Hypertensive patients on treatment with good control of blood pressure
- Registration Number
- CTRI/2013/06/003741
- Lead Sponsor
- nil
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 90
Ninety patients of ASA physical status II & III, of either sex, aged between 35-65 years and undergoing elective surgery requiring general anaesthesia will be included in the study. Controlled hypertensive patients with blood pressure less than 160/100 mmHg receiving oral antihypertensive medication for a minimum period of six weeks will be studied.
?Patients with anticipated difficult intubation
?Physical status > ASAIII
?Hiatus hernia, gastro-oesophageal reflux disease
?Obesity ( BMI > 30 kg/m2)
?Those on long-term sedatives, hypnotics, antidepressants, drugs affecting nervous system
?Previous myocardial infarction or angina pectoris, congestive heart failure
? Heart blocks
?Neurosurgical patients
?History of allergy to dexmedetomidine or esmolol
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method