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Comparison of analgesic effect of dexemedetomidine & ketamine with dexemedetomidine in mechanically ventilated patients

Not yet recruiting
Conditions
Medical and Surgical,
Registration Number
CTRI/2023/06/054139
Lead Sponsor
Dr Babaloo Kumar Singh
Brief Summary

The objective of this study is to evaluate dexmedetomidine in comparison to combination of ketamine and dexmedetomidine (KETODEX) in analgesia for elective post-operative mechanical ventilation after major surgery . We also want to compare time to extubation, duration of ICU stay, pain scores, side effect profiles, and patient satisfaction with the two regimens.

Detailed Description

Not available

Recruitment & Eligibility

Status
Not Yet Recruiting
Sex
All
Target Recruitment
120
Inclusion Criteria

1.Patients of ASA physical status 1 and 2 2.Patients between 18-60 years of age of either sex 3.Patients undergoing major abdominal surgery shifted to the ICU for elective ventilation.

Exclusion Criteria
  • 1.Patients who were pregnant or nursing; or had abnormal laboratory test results, significant psychiatric, neurological, cardiovascular, renal, or hepatic diseases.
  • 2.Patients on Neuromuscular blocking agents.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Comparison of Dexmedetomidine with combination of ketamine & dexmedetomidine in analgesia for elective post-operative mechanical ventilation after major surgery Analgesia defined as BPS score 5.1 year
Secondary Outcome Measures
NameTimeMethod
Sedation score (till extubation)Time to Extubation

Trial Locations

Locations (1)

Indira Gandhi Institute of Medical Sciences, Patna

🇮🇳

Patna, BIHAR, India

Indira Gandhi Institute of Medical Sciences, Patna
🇮🇳Patna, BIHAR, India
Dr Babaloo kumar Singh
Principal investigator
8252631393
bablu2k10skmc@gmail.com

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