Comparison of analgesic effect of dexemedetomidine & ketamine with dexemedetomidine in mechanically ventilated patients
- Conditions
- Medical and Surgical,
- Registration Number
- CTRI/2023/06/054139
- Lead Sponsor
- Dr Babaloo Kumar Singh
- Brief Summary
The objective of this study is to evaluate dexmedetomidine in comparison to combination of ketamine and dexmedetomidine (KETODEX) in analgesia for elective post-operative mechanical ventilation after major surgery . We also want to compare time to extubation, duration of ICU stay, pain scores, side effect profiles, and patient satisfaction with the two regimens.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 120
1.Patients of ASA physical status 1 and 2 2.Patients between 18-60 years of age of either sex 3.Patients undergoing major abdominal surgery shifted to the ICU for elective ventilation.
- 1.Patients who were pregnant or nursing; or had abnormal laboratory test results, significant psychiatric, neurological, cardiovascular, renal, or hepatic diseases.
- 2.Patients on Neuromuscular blocking agents.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Comparison of Dexmedetomidine with combination of ketamine & dexmedetomidine in analgesia for elective post-operative mechanical ventilation after major surgery Analgesia defined as BPS score 5. 1 year
- Secondary Outcome Measures
Name Time Method Sedation score (till extubation) Time to Extubation
Related Research Topics
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Trial Locations
- Locations (1)
Indira Gandhi Institute of Medical Sciences, Patna
🇮🇳Patna, BIHAR, India
Indira Gandhi Institute of Medical Sciences, Patna🇮🇳Patna, BIHAR, IndiaDr Babaloo kumar SinghPrincipal investigator8252631393bablu2k10skmc@gmail.com