Assessment of Respiratory Functions, Functional Capacity, Posture, and Quality of Life in Pectus Excavatum and Pectus Carinatum Deformities
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 186
- Locations
- 1
- Primary Endpoint
- Forced Vital Capacity (FVC)
Study Overview
Brief Summary
Pectus excavatum (PE) and pectus carinatum (PC) are chest wall deformities that may influence respiratory function, physical capacity, posture, and quality of life. This observational, cross-sectional study aims to provide a comprehensive and multidimensional evaluation of children with PE and PC and compare their findings with healthy controls. By examining multiple aspects of respiratory and physical function, postural characteristics, and quality of life, the study seeks to provide a broader understanding of the overall impact of these deformities.
Study Design
- Study Type
- Observational
- Observational Model
- Other
- Time Perspective
- Cross Sectional
Eligibility Criteria
- Ages
- 10 Years to 18 Years (Child, Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Individuals aged 10-18 years with pectus excavatum
- •Individuals aged 10-18 years with pectus carinatum
- •Healthy volunteers aged 10-18 years
Exclusion Criteria
- •Previous conservative or surgical treatment for pectus excavatum
- •Major surgery within the previous 6 months
- •Congenital or acquired cardiac disease
- •Congenital or acquired pulmonary disease
- •Neuromuscular or orthopedic disease
- •Connective tissue disorders (Marfan syndrome, Turner syndrome, neurofibromatosis, or tuberous sclerosis)
- •Diagnosed psychological or cognitive problems
- •Obesity or severe underweight (BMI below the 5th percentile or above the 95th percentile)
- •Hearing or visual impairment not corrected with hearing aids or glasses
- •Acute infection, including an acute respiratory tract infection within the previous 2 weeks
Arms & Interventions
Healthy Control Group
Age-matched healthy participants without pectus deformity
Pectus Excavatum Group
Participants diagnosed with pectus excavatum
Pectus Carinatum
Participants diagnosed with pectus carinatum
Outcomes
Primary Outcomes
Forced Vital Capacity (FVC)
Time Frame: Baseline
Forced vital capacity (FVC) was assessed using spirometry and expressed as a percentage of the predicted value.
Forced Expiratory Volume in One Second (FEV1)
Time Frame: Baseline
Forced expiratory volume in one second (FEV1) was assessed using spirometry and expressed as a percentage of the predicted value.
FEV1/FVC Ratio
Time Frame: Baseline
The FEV1/FVC ratio was assessed using spirometry and expressed as a percentage of the predicted value.
Maximal Voluntary Ventilation (MVV)
Time Frame: Baseline
Maximal voluntary ventilation (MVV) was assessed using spirometry and expressed as a percentage of the predicted value.
Secondary Outcomes
- Handgrip Strength(Baseline)
- Respiratory Muscle Strength(Baseline)
- Physical Activity Level(Baseline)
- Aerobic Capacity(Baseline)
- Body Composition(Baseline)
- Neck and Trunk Muscle Strength(Baseline)
- Muscle Endurance - Sit-Up Test(Baseline)
- Muscle Endurance - Trunk Lift Test(Baseline)
- Muscle Endurance - Push-Up Test(Baseline)
- Flexibility(Baseline)
- Posture(Baseline)
- Health-Related Quality of Life Assessed by the Nuss Questionnaire(Baseline)