IRCT2016041016473N7已完成2 期
Effect of N-Acetyl Cysteine on liver and kidney function tests after surgical bypass in obstructive jaundice patients
Tabriz University of Medical Science0 个研究点目标入组 30 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 75 years（—）
- 性别
- All
入选标准
- •Age above 18 years and below 75; unable to treta with ERCP or radiologic intervention; common bile diameter over 10 mm; no indication for resection of obstructive jaundice (choledochal cyst or Whipple procedure); bilirubin level over 5 mg/dl
- •Exclusion criteria: possibility of surgical resection (Whipple procedure or bile duct tumor resection); any contraindication for acetylcysteine injection (e.g. asthma, bronchospasm, angioedema or known hypersensitivity); liver cirrhosis or need for liver transplant according to clinical or surgical findings for any reason; known renal failure or heart failure; need for mechanical ventilation before surgery, septic shock resistant to inotrope ( Systolic blood pressure less than 90) before surgery; preoperative biliary drainage by ERCP or radiologic intervention; liver enzymes (ALT, AST) greater than 10 times the normal; acute viral hepatitis or any history of drug toxicity; known liver disease such as autoimmune hepatitis; hemolysis cases
排除标准
- 未提供
研究者
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