Effects of Cognitive Training on Speech Perception

Not Applicable

Terminated

• Conditions: Deafness and Auditory Perception; Hearing Loss
• Interventions: Behavioral: Cognitive training

• Registration Number: NCT02294812
• Lead Sponsor: Aaron Newman

Brief Summary

In this study, the investigators are testing whether cognitive training can lead to improvements in speech perception for individuals with hearing loss. Individuals will complete 20 hours of cognitive training that is designed to improve cognitive abilities such as short term memory and attention. The investigators predict that cognitive training that improves the cognitive abilities affected by hearing loss will improve speech perception.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2014-11-03
• Study First Submitted QC: 2014-11-17
• Study First Posted: 2014-11-19
• Study Start: 2016-09
• Primary Completion: 2020-09
• Study Completion: 2020-09
• Status Verified: 2021-01
• Last Update Submitted: 2021-01-26
• Last Update Posted: 2021-01-27

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 42

Inclusion Criteria

• Able to come to Dalhousie University, Halifax, Nova Scotia, Canada for study visits
• Adults (50 years or older) with mild to moderate hearing loss
• Access to an internet-connected device that is able to use Flash media, basic computer skills
• Medically stable participants
• Not currently taking medication that may affect brain function (e.g., anti-anxiety medication)
• Normal or corrected-to-normal vision

Exclusion Criteria

• Participants with neurological conditions such as epilepsy or concussions will be excluded for safety reasons
• Participants who are not native English speakers (materials used in the study are only in English)
• Participants who are unable to provide consent
• Participants with impaired cognition (assessed with the Montreal Cognitive Assessment)
• Participants with high accuracy on the Speech Perception in Noise task at the second study visit (to eliminate participants who may be performing at ceiling level)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Control, cognitive training	Cognitive training	Participants in the control arm will receive cognitive training for cognitive abilities not affected by age-related hearing loss.
Active Control, crossword training	Cognitive training	Participants in this group will undergo crossword puzzle training. The purpose of this group is control for any effects that may be due to engaging in cognitive training.
Experimental, cognitive training	Cognitive training	Participants in the experimental arm will receive cognitive training for cognitive abilities affected by age-related hearing loss.

Primary Outcome Measures

Name	Time	Method
Speech Perception in Noise Test - Improvement in speech perception accuracy from baseline to post-training for high and low predictability sentences	Baseline, Weeks 2, 10, and 18	Sentences of high predictability and low predictability are played with multi-user talker babble. Participants must repeat the last word of each sentence as they heard it. The primary outcome measure will be the accuracy for repeating the sentence.

Secondary Outcome Measures

Name	Time	Method
Working Memory Cognitive Training - Improvements in working memory abilities from baseline	Weeks 2, 10, and 18	Individuals are asked to participate in 20 hours of cognitive training that will focus on either improving abilities affected by hearing loss (i.e., verbal working memory), or abilities not affected by hearing loss (i.e., spatial working memory).; Performance on the working memory task, Operation Span Task (OSPAN), will be assessed using the total score which is calculated as a sum based on the number of correct answers (letters accurately sequentially recalled) within a block for the duration of the task. Higher scores indicate better working memory capacity. Performance on the working memory cognitive training games will be assessed using the participant's accuracy, reaction time, and final score on the game.; Improvements in working memory will be assessed by comparing participant performance on working memory tasks (OSPAN; cognitive training memory games) before receiving cognitive training, immediately after receiving cognitive training, and eight weeks post-training.
Brain Performance Test	Weeks 2 and 10	The Brain Performance Test (BPT) is an assessment tool available online through the training program website. Participants will be assessed at home on their initial performance for a variety of cognitive abilities including stop-signal tasks, grammatical reasoning, and memory spans. After completing the eight weeks of cognitive training, participants will again be assessed at home with the BPT to determine whether there are any improvements in cognitive abilities.
Attention Cognitive Training - Improvements in attention abilities from baseline	Weeks 2, 10, and 18	Individuals are asked to participate in 20 hours of cognitive training. Cognitive training will focus on either improving abilities affected by hearing loss (i.e., attention), or abilities not affected by hearing loss (i.e., spatial working memory).; Performance on the attention task, Flanker-Simon, will be assessed based on participant's accuracy and reaction time for the Flanker task, and the Simon task.; Performance on the attention cognitive training games will be assessed using the participant's accuracy, reaction time, and final score on the game.; Improvements in attention will be assessed by comparing the performance of participants on attention tasks (Flanker-Simon; cognitive training attention games) before receiving cognitive training, immediately after receiving cognitive training, and eight weeks post-training.

Trial Locations

Locations (1)

NeuroCognitive Imaging Lab, Dalhousie University; 🇨🇦 Halifax, Nova Scotia, Canada