Simultaneous right heart cauterisation and echocardiography in patients with pulmonal arterial hypertension to validate the non-invasive deformation-area loop

Completed

• Conditions: increased pressure in the pulmonal artery; Pulmonary arterial hypertension; 10019280

• Registration Number: NL-OMON44427
• Lead Sponsor: Fysiologie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

Suspected pulmonary arterial hypertension
Above 18 years
Voluntary participation

Exclusion Criteria

Cardiovascular diseases, other than pulmonary arterial hypertension
Diabetes Mellitus

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary study parameters are the correlation between the different measures<br /><br>for contractility and compliance from the strain-area loop and the<br /><br>pressure-volume loop.<br /><br><br /><br>• The relation between the end-systolic pressure-volume relationship (ESPVR)<br /><br>the slope of the systolic part of the strain-area loop (Sslope).<br /><br>• The relation between the end-diastolic pressure-volume relationship (EDPVR)<br /><br>the slope of the diastolic part of the strain-area loop during passive filling. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>• dP/dT of the pressure-volume loop<br /><br>• de maximale eind-systolische strain </p><br>