Effects of Cichorium Intybus L. Leaf Extract on improvement of the clinical status of patients with periodontal
Phase 3
- Conditions
- periodental.Periodontal disease, unspecified
- Registration Number
- IRCT2015112825274N1
- Lead Sponsor
- Vice chancellor for research of Arvand International Division of Ahvaz Jundishapur University of Med
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
age over 30 years; having periodontal disease (PPD more than 4 millimeter) in at least one site in the three quarters of the mouth); BMI more than 18.5 Kilogram/ square meter. Exclusion criteria: lack of cooperation; pregnancy and lactation; smoking; use of dietary supplements and antioxidant; Consumption of anti cariogenic gum; Consumption of drugs that suppress the immune system; changes in diet pattern and hyperlipidemia.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Interleukin-6. Timepoint: Before and two months after intervention. Method of measurement: ELISA.;Hs-CRP. Timepoint: Before and two months after intervention. Method of measurement: ELISA.;Malon de aldehid (MDA). Timepoint: Before and two months after intervention. Method of measurement: chemical method (Kit).;Blood uric acid. Timepoint: Before and two months after intervention. Method of measurement: chemical method.;Triglycerides. Timepoint: Before and two months after intervention. Method of measurement: Enzymatic.;Cholesterol. Timepoint: Before and two months after intervention. Method of measurement: Enzymatic.;HDL-cholesterol. Timepoint: Before and two months after intervention. Method of measurement: Enzymatic.;Total antioxidant capacity of blood. Timepoint: Before and two months after intervention. Method of measurement: Enzymatic.
- Secondary Outcome Measures
Name Time Method