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This study is designed to know the characterestics of heart failure and to determine role of AST/ALT ratio in the severity of heart failure

Not yet recruiting
Conditions
Heart failure, unspecified,
Registration Number
CTRI/2023/03/050230
Lead Sponsor
Varun Anil Parmar
Brief Summary

Heart failure is a commonly encountered syndrome in clinical practice. It is important to identify and lay out the clinical profile of the same-to assist in the timely detection and treatment of the same and recognition of risk factors for same. There is also an ever-present need to identify relatively inexpensive biomarkers and investigation of AST/ALT ratio for same is a promising approach. This research project aims to address these issues.

After CTRI registration, participant selection will be carried out as per criteria-consent shall be taken and following which they will be subjected to questionnaire based on which data sets will be compiled and analysed

Detailed Description

Not available

Recruitment & Eligibility

Status
Not Yet Recruiting
Sex
All
Target Recruitment
86
Inclusion Criteria

Heart failure with reduced ejection fraction 2.

Exclusion Criteria
  • Primary liver disease 2.
  • Renal failure 3.
  • Pregnancy 6.
  • Malignancy 7.
  • Muscle injury 8.
  • Recent surgery 9.
  • History of significant alcohol usage 10.
  • Hepatotoxic drugs 11.

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
AST/ALT ratio relation to severity of Heart FailureCross sectional study involving each patient at presentation | Data will be compiled at end of study i.e. 22 months
Secondary Outcome Measures
NameTimeMethod
Clinical Profile of Heart FailureData to be compiled at end of study

Trial Locations

Locations (1)

Kasturba Hospital, Manipal

🇮🇳

Udupi, KARNATAKA, India

Kasturba Hospital, Manipal
🇮🇳Udupi, KARNATAKA, India
Varun Parmar
Principal investigator
9769484625
parmar.anil@learner.manipal.edu

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