Effect of Gestational Diabetes Mellitus on Serum Hormone Levels and Human Milk Composition
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Serum hormone levels
研究概览
简要总结
This study aims to compare hormone levels and milk composition in women with and without gestational diabetes through postpartum human milk and blood samples.
详细描述
Pregnant women with GDM who received medical nutrition therapy and healthy controls were evaluated on postpartum days 14 and 30. Human milk and blood samples, as well as 3-day food consumption records, were collected. Levels of insulin, adiponectin, leptin, ghrelin, chemerin, and dermcidin in blood and milk were measured and compared with macronutrient contents of milk.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Voluntary pregnant women with singleton pregnancies
- •No complications or chronic diseases.
排除标准
- •With pregnant and post-partum complications or chronic diseases
- •Mothers who feed their babies with formula
结局指标
主要结局
Serum hormone levels
时间窗: Postpartum day 14 and 30
Measurement of insulin, adiponectin, leptin, ghrelin, chemerin, and dermcidin levels using ELISA in maternal blood serum
Human milk hormone levels
时间窗: Postpartum day 14 and 30
Measurement of insulin, adiponectin, leptin, ghrelin, chemerin, and dermcidin levels using ELISA in human milk samples
次要结局
- Human milk energy and macronutrient content(Postpartum day 14 and 30)
研究者
Sule Aktac
Assoc. Prof. Dr.
Marmara University