NL-OMON56427
Recruiting
Phase 4
Clinical Outcome and Cost-effectiveness of Reduced Noradrenaline by Using a Lower Blood Pressure Target in Patients with Cardiogenic Shock from Acute Myocardial Infarction: A Multicenter Randomized Trial - NORSHOCK
Overview
- Phase
- Phase 4
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Cardiologie
- Enrollment
- 776
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •'Planned early revascularization'
- •'Systolic blood pressure \<90mmHg for \> 30minutes, OR use of drugs to maintain
- •SBP\>90 mmHg at presentation before randomization'
- •'Signs of pulmonary congestion'
- •'4\. Signs of impaired organ perfusion with at least one of the following
- •a) Altered mental status
- •b) Cold, clammy skin and extremities
- •c) Oliguria with urine output \<30ml/hour
- •d) Serum lactate \>2\.0 mmol/L'
Exclusion Criteria
- •'Resuscitation \>30 minutes'
- •'No intrinsic heart action'
- •'Cerebral deficit with fixed dilated pupils (not drug\-induced)'
- •'Mechanical cause of cardiogenic shock'
- •'Onset of shock \>12 hours'
- •'Massive lung embolism'
- •'Shock due to other cause (bradycardia, sepsis, hypovolemia, etc.)'
Outcomes
Primary Outcomes
Not specified
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