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Clinical Trials/NCT03481296
NCT03481296
Completed
Not Applicable

Culturally Adapted Multilevel Decision Support Navigation Trial To Reduce Colorectal Cancer Disparity Among At-Risk Asian American Primary Care Patients

University of California, Irvine1 site in 1 country400 target enrollmentAugust 20, 2018

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Colorectal Cancer
Sponsor
University of California, Irvine
Enrollment
400
Locations
1
Primary Endpoint
Colorectal cancer screening test-specific adherence at 6 months (Stool Blood Test)
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

The objective of the study is to conduct a randomized controlled trial to determine the impact of a multi-level culturally-sensitive decision support intervention on colorectal cancer screening adherence among 400 Chinese and Korean American primary care patients.

Detailed Description

This study culturally adapts existing evidence-based decision support navigation intervention and tests its efficacy among 200 Chinese and Korean American men and 200 Chinese and Korean American women aged 50 to 75 eligible for colorectal cancer screening. Participants are recruited from primary care physician clinics. The study is designed to compare colorectal cancer screening outcomes between the decision support navigation intervention and the advanced control. Those randomized to the advanced control group only receives an informational booklet, a stool blood test kit and a reminder by mail. Those randomized to the decision support navigation intervention group receives everything the advanced control group receives as well as decision support and navigation contacts. Investigators in the study develop an individualized screening plan using a theory-based online Decision Counseling Program, share the plan with the participants' primary care physicians, and have primary care physicians to encourage the colorectal cancer screening to participants. Using outcomes data collected by survey and medical record review, this study: (1) determines overall colorectal cancer screening adherence in the culturally adapted decision support navigation intervention vs. the advanced control; (2) measures change in colorectal cancer screening decision stage in the culturally adapted decision support navigation intervention vs. the advanced control; and (3) assesses colorectal cancer screening test-specific (stool blood test vs. colonoscopy) adherence in the culturally adapted decision support navigation intervention vs. the advanced control. Additionally, investigators in the study evaluate intervention reach, effectiveness, adoption, implementation, and maintenance using interview data.

Registry
clinicaltrials.gov
Start Date
August 20, 2018
End Date
June 30, 2021
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Sunmin Lee

Professor

University of California, Irvine

Eligibility Criteria

Inclusion Criteria

  • Male and female Chinese and Korean American patients aged 50 to 75, who are not up to date for colorectal cancer screening

Exclusion Criteria

  • Those with a family history, previous history of removing polyps, inflammatory bowel disease, or diagnosis of colorectal cancer screening.

Outcomes

Primary Outcomes

Colorectal cancer screening test-specific adherence at 6 months (Stool Blood Test)

Time Frame: 6 months

Measure the fraction of participants who undergo a stool blood test at 6 months.

Colorectal cancer screening test-specific adherence at 12 months (Colonoscopy)

Time Frame: 12 months

Measure the fraction of participants who undergo a colonoscopy at 12 months.

Colorectal cancer screening adherence at 6 months by self-report

Time Frame: 6 months

Measure overall colorectal cancer screening adherence at 6 months by self-report during 6-month survey (by phone).

Colorectal cancer screening decision stage at baseline (Stool Blood Test)

Time Frame: Baseline

Measure colorectal cancer screening decision stage for stool blood test at baseline.

Colorectal cancer screening decision stage at baseline (Colonoscopy)

Time Frame: Baseline

Measure colorectal cancer screening decision stage for colonoscopy at baseline.

Colorectal cancer screening decision stage at 6 months (Colonoscopy)

Time Frame: 6 months

Measure colorectal cancer screening decision stage for colonoscopy at 6 months.

Change in colorectal cancer screening decision stage between baseline and 6 months (Colonoscopy)

Time Frame: Baseline and 6 months

Measure change in colorectal cancer screening decision stage for colonoscopy between baseline and 6 months.

Overall colorectal cancer screening adherence at 12 months by self-report

Time Frame: 12 months

Measure overall colorectal cancer screening adherence at 12 months by self-report (by phone interview).

Change in colorectal cancer screening decision stage between baseline and 6 months (Stool Blood Test)

Time Frame: Baseline and 6 months

Measure change in colorectal cancer screening decision stage for stool blood test between baseline and 6 months.

Colorectal cancer screening adherence at 6 months by medical record review

Time Frame: 6 months

Measure overall colorectal cancer screening adherence at 6 months by medical record review.

Overall colorectal cancer screening adherence at 12 months by medical record review

Time Frame: 12 months

Measure overall colorectal cancer screening adherence at 12 months by medical record review.

Colorectal cancer screening test-specific adherence at 6 months (Colonoscopy)

Time Frame: 6 months

Measure the fraction of participants who undergo a colonoscopy at 6 months.

Colorectal cancer screening test-specific adherence at 12 months (Stool Blood Test)

Time Frame: 12 months

Measure the fraction of participants who undergo a stool blood test at 12 months.

Colorectal cancer screening decision stage at 6-months (Stool Blood Test)

Time Frame: 6 months

Measure colorectal cancer screening decision stage for stool blood test at 6 months.

Secondary Outcomes

  • Knowledge about colorectal cancer and colorectal cancer screening (Baseline)(Baseline)
  • Knowledge about colorectal cancer and colorectal cancer screening (6 months)(6 months)
  • Change in knowledge about colorectal cancer and colorectal cancer screening between baseline and 6 months(Baseline and 6 months)

Study Sites (1)

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