Altered PSA Test Due to Possible Suspected Heterophilic Antibodies
Terminated
- Conditions
- PSA
- Registration Number
- NCT02455466
- Lead Sponsor
- University of Zurich
- Brief Summary
The purpose of this study is to investigate if clinically non explainable high or low Prostate-specific antigen (PSA) levels are associated with heterophilic antibodies in the serum of participants. The investigators will examine if heterophilic antibodies are the reasons of altered PSA levels.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- Male
- Target Recruitment
- 50
Inclusion Criteria
- Male, with a a clinically high or low unexplainable PSA measurement
- Age between 40 and 90 years
- Written informed consent
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Exclusion Criteria
- Female
- No PSA measurement available or planned
- Age over 90 or under 40 years
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Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Presence of heterophilic antibodies in the serum of participants 1.5 years Heterophilic antibodies will be measured in the Blood serum of participants by sandwich Elisa assay
Altered PSA levels due to the Presence of Heterophilic antibodies 1.5 years If heterophilic antibodies were present in the serum of the participant, another PSA test will be ran after absorbance of heterophilic antibodies to investigate whether PSA levels are changed without the presence of heterophilic antibodies
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University Hospital Zürich
🇨🇭Zürich, Switzerland