Immunity against vaccine-preventable diseases in the homeless population in Germany

Recruiting

• Conditions: B15; B18; A36; A35; B05; B26; B06; Acute hepatitis A; Chronic viral hepatitis; Diphtheria

• Registration Number: DRKS00016336
• Lead Sponsor: Klinik für Allgemeine Innere Medizin, Gastroenterologie, Hepatologie, Infektiologie und PneumologieKatharinenhospital Stuttgart/Klinikum Stuttgart

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-02-22
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 500

Inclusion Criteria

Homelessness currently or in the last 12 months
Minimum age of 18 years
Suitability to donate blood (max. 30ml)
Ability to consent

Exclusion Criteria

Not provided

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary outcome is to determine the status of immunity as a percentage for the following diseases in the homeless population in Germany:<br>Hepatitis A<br>Hepatitis B<br>Diphtheria<br>Tetanus<br>Measles<br>Mumps<br>Rubella<br>Varicella

Secondary Outcome Measures

Name	Time	Method
The secondary outcome is the determination of anti-Hbc and Hbs antigen in order to be able to identify an existing chronic hepatitis B in the homeless. Thereby, a distinction can be made between vaccination and infection.<br><br>Biographical data are requested using case history forms, so that any existing vaccination gaps can be associated with them. We will also examine whether there is an association between age, gender, origin, illicit drug use, duration of homelessness, incarceration and pre-existing conditions and vaccination gaps.