The Effects of a 16-Week Individualized, Intensive Strength Training Program in Patients With Rheumatoid Arthritis

Not Applicable

Completed

• Conditions: Rheumatoid Arthritis

• Registration Number: NCT00327275
• Lead Sponsor: University of Arizona

Brief Summary

To assess the effects of a 16-week individualized, intensive strength training program in patients with rheumatoid arthritis. Primary and secondary outcomes include: strength and body composition, function, disease activity, pain, quality of life.

We hypothesized that improvements would be seen in all of the above outcomes.

Detailed Description

Not available

Study Timeline

• Study Start: 2004-03
• Study Completion: 2005-01
• Status Verified: 2006-05
• Study First Submitted: 2006-05-16
• Study First Submitted QC: 2006-05-16
• Last Update Submitted: 2006-05-16
• Study First Posted: 2006-05-18
• Last Update Posted: 2006-05-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 35

Inclusion Criteria

• Males and females with RA
• Over 18 years of age
• ACR Functional Class I and II
• Taking Remicade >4 months

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Exclusion Criteria

• Presence of comorbid conditions contraindicated to exercise, including, but not limited to:

  1. heart disease
  2. severe osteoporosis: (if >50 years): T score < -3.0 for hip or spine excluded; T score <-2.5 for hip or spine w/o current treatment)
  3. (all potential subjects) previous non-traumatic fractures
  4. uncontrolled BP

• BMI >40

• Regular use of assistive walking device which would interfere with ability to lift weights

• Currently or within the last 3 months participating in aerobic exercise > 150 minutes a week

• Currently or within the last 3 months participating in any regular strength training activities

• Presence of neurological impairment that directly limits ability to perform exercise

• Participation in concurrent exercise study

• Any reason for which the investigator deems it would not be in the patient's best interest to continue in the study

• Plans to move away from site within next 1 year

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Strength
Body Composition
Function
Pain

Secondary Outcome Measures

Name	Time	Method
Quality of Life
Disease Activity
Fatigue

Trial Locations

Locations (1)

University of Arizona; 🇺🇸 Tucson, Arizona, United States