Effective Rehabilitation of Patients Operated With Total Knee Arthroplasty

Not Applicable

Completed

• Conditions: Osteoarthritis
• Interventions: Other: Maximal strength training

• Registration Number: NCT01877733
• Lead Sponsor: Norwegian University of Science and Technology

Brief Summary

The purpose of this study is to investigate the effect of maximal strength training (MST) compared to standard rehabilitation in patients operated with total knee arthroplasty. Previous studies report reduced physical function and muscle strength despite successful surgery inserting an artificial implant.

Furthermore, great loss of muscle strength has been found in these patients in the early postoperative phase.

The study is a randomized controlled trial. The investigators hypothesize that MST will increase muscle strength and physical function more than standard rehabilitation.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-01
• Study First Submitted: 2013-04-16
• Study First Submitted QC: 2013-06-11
• Study First Posted: 2013-06-14
• Primary Completion: 2015-07
• Study Completion: 2015-07
• Status Verified: 2020-04
• Last Update Submitted: 2020-04-20
• Last Update Posted: 2020-04-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 41

Inclusion Criteria

• unilateral osteoarthritis,
• < 75 years

Exclusion Criteria

• disease(s) that compromise testing/training,
• unable to understand written and verbal instructions and information,
• osteoarthritis in the contralateral leg that needs treatment.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Maximal strenght training	Maximal strength training	Training maximal strength training 3 times a week/1 physiotherapy session for 8 weeks

Primary Outcome Measures

Name	Time	Method
Muscle strength in leg extension and leg press	Measured preoperatively, after 7 days, 10 wks and 1 year	Measured preoperatively implies measuring the outcome within the last month prior to surgery

Secondary Outcome Measures

Name	Time	Method
6 minute walk test	preopertively, 7 days postoperatively and after 1 year	Measuring the outcome preoperatively implies testing within the last month prior to surgery
EQ-5D (measure of health outcome)	Preoperatively (within 1 month prior to surgery), 7 days, 10 wks and 1 year postoperatively
KOOS; Knee injury and osteosarthritis outcome score	Preoperatively (within 1 month prior to surgery), 7 days postoperatively and 10 wks and 1 year postoperatively
VAS scale recording pain	preoperatively (within 1 month prior to surgery), 7 days, 10 wks and 1 year postoperatively

Trial Locations

Locations (1)

St. Olavs hospital; 🇳🇴 Trondheim, Norway