Dairy Versus Plant-based Beverages Combined With Resistance-training for Improving Bone Health
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- Change in section modulus at the hip (cm to the power of 3)
研究概览
简要总结
This study will evaluate the effects of consuming dairy milk versus two plant-based beverages (pea-based, and almond-based) after resistance training sessions (3 times per week for 12 months) on bone properties (bone mineral density, bone geometry), body composition, strength, and functional performance in post-menopausal women and men 50y and older.
详细描述
The purpose of the study is to compare consumption of dairy milk (1% chocolate milk) to plant-based beverages (protein-matched pea beverage and low-protein almond beverage) after resistance-training sessions on bone mineral density, bone geometric properties, lean tissue and fat mass, muscular strength, and functional performance. One-hundred and fifty postmenopausal women and men 50y or older will be randomized to one of three groups: 1) Dairy milk; 2) pea-beverage; 3) almond beverage. The study will be double-blind, accomplished by chocolate flavoring of each beverage. Participants will do supervised strength-training sessions three times per week for 12 months. After each strength-training session, participants will consume 375 ml of their beverage and then consume 375 ml of their beverage again one hour later.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Women need to be postmenopausal (no age limit)
- •Men need to be 50y or older
排除标准
- •Taking medications that might affect bone
- •Conditions that might preclude participating in a resistance-training program (determined by the "Get Active Questionnaire").
- •Planning 6 weeks of travel during the 12 month intervention period
- •Planning major surgery during the 12 month intervention period
- •Already strength training greater than 2 days per week for 30 minutes or longer per session
- •Allergies to ingredients in the beverages
研究组 & 干预措施
1% chocolate milk
375 ml of 1% chocolate milk consumed immediately after resistance training sessions + 375 ml of chocolate milk consumed 1 hour after resistance training sessions
干预措施: Nutritional supplementation during a 12 month resistance training program (Dietary Supplement)
Pea-based beverage
375 ml of pea beverage consumed immediately after resistance training sessions + 375 ml of pea beverage consumed 1 hour after resistance training sessions
干预措施: Nutritional supplementation during a 12 month resistance training program (Dietary Supplement)
Almond beverage
375 ml of almond beverage consumed immediately after resistance training sessions + 375 ml of almond beverage consumed 1 hour after resistance training sessions
干预措施: Nutritional supplementation during a 12 month resistance training program (Dietary Supplement)
结局指标
主要结局
Change in section modulus at the hip (cm to the power of 3)
时间窗: 12 months
Section modulus measured by dual energy X-ray absorptiometry
次要结局
- Change in knee extension strength (kg)(6 and 12 months)
- Change in hip bone mineral density (g/cm-squared)(12 months)
- Change in cross-sectional area at the hip (cm-squared)(12 months)
- Change in cortical thickness at the hip (cm)(12 months)
- Change in buckling ratio at the hip (no units)(12 months)
- Change in bench press strength (kg)(6 and 12 months)
- Change in lean tissue mass (kg)(12 months)
- Change in fat mass (kg)(12 months)
- change in 30 second sit to stand (number of repetitions)(6 and 12 months)
- Change in walking speed (m/s)(6 and 12 months)
- Change in timed up and go performance (s)(6 and 12 months)
- Change in lumbar spine bone mineral density (g/cm-squared)(12 months)
研究者
Phil Chilibeck
Professor
University of Saskatchewan