Application and Clinical Evaluation of Longitudinal Chromatic Aberration Technique in Ophthalmology
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 21
- 试验地点
- 1
- 主要终点
- Ocular Fundus Blood Flow
研究概览
简要总结
Our study aims to delve into the effects of shifting the focal point of blue light from video or text displayed on a terminal screen forward on the axial length of the eye, ocular blood flow, visual fatigue, and visual function, that is, its relationship with Video Display Terminal (VDT) syndrome and myopia. By examining the decoding ability of the adult subjects' retina to the clarity of the signal, we will attempt to develop a novel, non-invasive strategy to curb the elongation of the eyeball associated with myopia. Concurrently, we will also focus on the pathophysiological mechanisms underlying VDT syndrome and explore its potential link to the progression of myopia, providing new scientific evidence for the prevention and treatment of this ocular condition. This research is expected to provide robust support for addressing the global issue of myopia and the health challenges posed by VDT syndrome. Ultimately, by integrating global eye health issues with the challenges brought about by VDT syndrome, we will propose intervention and prevention strategies, offering new insights for the advancement of ophthalmology and public health sectors, thereby promoting visual acuity and ocular health for the population.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Adult population, regardless of gender
- •Refractive error is less than or equal to -2.5D and both eyes achieve corrected visual acuity of 0.8 or higher.
- •Normal intraocular pressure with no organic pathology.
- •No apparent symptoms of dry eye.
- •Willing to cooperate to complete all the tests.
- •Voluntarily signing the informed consent form.
排除标准
- •Individuals with strabismus and amblyopia exist.
- •Suffering from congenital eye conditions such as congenital cataracts or congenital retinal diseases.
- •Those who have undergone intraocular surgery (such as cataract removal, intraocular lens implantation, etc.).
- •Individuals with refractive media opacity (such as corneal lesions, lens opacity, etc.).
- •Abnormal intraocular pressure (IOP) (IOP < 10 mmHg or IOP > 21 mmHg, or a bilateral IOP difference of ≥5 mmHg).
- •Only one eye meets the inclusion criteria.
- •Active corneal infections such as bacterial, fungal, viral, or other acute or chronic anterior segment inflammations.
- •Currently using medications that may lead to dry eye or affect vision and corneal curvature.
- •Other ocular conditions, such as dacryocystitis, eyelid disorders and abnormalities, abnormal intraocular pressure, and glaucoma.
- •Unable to undergo regular eye examinations.
结局指标
主要结局
Ocular Fundus Blood Flow
时间窗: The total duration of the visual task is 50 minutes. Retinal blood flow is measured for each subject at 0 minutes, 25 minutes, and 50 minutes during the visual task, resulting in a
The study measured the sub foveal choroidal thickness, superficial vessel complex (SVC) density, and deep vessel complex (DVC) density, analyzing changes in retinal blood flow under the two modes.
次要结局
- AC/A Ratio Measurement Post-VEP Tasks(Each participant will undergo five AC/A ratio measurements: at baseline and immediately after each of four VEP tasks.)
- Visual fatigue(Each participant will complete the visual fatigue questionnaire, followed immediately by a VEP task, and then re-assess visual fatigue immediately afterward. This sequence will occur twice per group, totaling eight assessments per participant.)
- Blink Frequency(Blink frequency 3 minutes after the start of each visual evoked task and 3 minutes before the end.)
- Measurement of Accommodative Sensitivity with Flip-Chart Post-VEP Tasks(Each participant will have five measurements: a baseline, and four post-VEP tasks, with immediate flipchart tests after each task.)
- Reading efficiency(The test was recorded 5 minutes after the start and 10 minutes before the end.)