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Clinical Trials/ISRCTN29654606
ISRCTN29654606
Active, not recruiting
未知

A multicentre randomised trial of surgical versus percutaneous revascularisation of ischaemic left ventricular dysfunction (iLVSD) in the United Kingdom, with embedded internal pilot and health economic analysis

niversity of Leicester0 sites630 target enrollmentJuly 17, 2024
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ConditionsHeart failureCirculatory System

Overview

Phase
未知
Intervention
Not specified
Conditions
Heart failure
Sponsor
niversity of Leicester
Enrollment
630
Status
Active, not recruiting
Last Updated
last year
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
July 17, 2024
End Date
March 1, 2032
Last Updated
last year
Study Type
Interventional
Sex
All

Investigators

Sponsor
niversity of Leicester

Eligibility Criteria

Inclusion Criteria

  • •1\. Age \>18 years
  • •2\. LVEF \<40% (quantified by any recognised imaging modality) within the last 12 months. If the patient has had an MI within the last 12 months post\-MI imaging is required with LVEF \<40%
  • •3\. Significant amount of myocardium at risk defined as coronary artery disease with BCIS myocardial jeopardy score \>6 on recent (\<6 months) coronary angiogram
  • •4\. Signed informed consent

Exclusion Criteria

  • •1\. Decompensated heart failure requiring inotropic support, invasive or non\-invasive ventilation or mechanical circulatory support less than 48 hours prior to randomisation
  • •2\. ST Elevation Myocardial Infarction (STEMI) \<72 hours
  • •3\. Valvular heart disease or any other cardiac conditions (e.g., LV aneurysm) requiring surgery
  • •4\. Pregnancy
  • •5\. Individuals who have declined access to Hospital Episode Statistics for research purposes
  • •6\. An inability to understand the languages in which the trial materials are provided

Outcomes

Primary Outcomes

Not specified

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