ISRCTN29654606Active, not recruitingUnknown
A multicentre randomised trial of surgical versus percutaneous revascularisation of ischaemic left ventricular dysfunction (iLVSD) in the United Kingdom, with embedded internal pilot and health economic analysis
niversity of Leicester0 sites630 target enrollmentStarted: July 17, 2024Last updated:
Conditions
Trial Snapshot
- Phase
- Unknown
- Status
- Active, not recruiting
- Sponsor
- Enrollment
- 630
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Sex
- All
Inclusion Criteria
- •1. Age >18 years
- •2. LVEF <40% (quantified by any recognised imaging modality) within the last 12 months. If the patient has had an MI within the last 12 months post-MI imaging is required with LVEF <40%
- •3. Significant amount of myocardium at risk defined as coronary artery disease with BCIS myocardial jeopardy score >6 on recent (<6 months) coronary angiogram
- •4. Signed informed consent
Exclusion Criteria
- •1. Decompensated heart failure requiring inotropic support, invasive or non-invasive ventilation or mechanical circulatory support less than 48 hours prior to randomisation
- •2. ST Elevation Myocardial Infarction (STEMI) <72 hours
- •3. Valvular heart disease or any other cardiac conditions (e.g., LV aneurysm) requiring surgery
- •4. Pregnancy
- •5. Individuals who have declined access to Hospital Episode Statistics for research purposes
- •6. An inability to understand the languages in which the trial materials are provided
Investigators
Similar Trials
Recruiting
Not Applicable
Multicenter prospective randomized study of surgical ablation for atrial fibrillation during non-mitral cardiac operatioatrial fibrillationJPRN-UMIN000016129The Cardiovascular Institute Academic Research Organization400
Completed
Phase 2
Reconstruction of major extensive facial burn injuriesFacial Burn.Burns and corrosionsT20, T21,IRCT201307319044N2Vice chancellor for research, Iran University of Medical Sciences60
Active, not recruiting
Unknown
A trial of surgery versus no surgery in patients with severe pectus excavatum: looking at improvements in heart and lung functioCardiothoracic surgery, pectus excavatumSurgeryISRCTN11359779South Tees Hospitals NHS Foundation Trust300
Completed
Phase 4
A comparative study between chest wall nerve block vs conventional IV analgesics for post-operative pain management in breast cancer patients undergoing modified radical mastectomy.CTRI/2023/10/058992Department of Anaesthesiology RIMS Ranchi60
Unknown
Phase 3
A randomized controlled trial to compare surgical effectiveness of tumor enucleation versus systematic segmentectomy for resecting hepatocellular carcinomaCases with hepatocellular carcinoma scheduled to undergo hepatic resection.JPRN-C000000086Department of Digestive Surgery, Nihon University School of Medicine120