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临床试验/NCT05558332
NCT05558332进行中(未招募)不适用

Youth Nominated Support Team for Suicidal Adolescents at Clinical High Risk for Psychosis

University of California, Irvine1 个研究点 分布在 1 个国家目标入组 70 人开始时间: 2025年3月12日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
进行中(未招募)
入组人数
70
试验地点
1
主要终点
Social Connectedness

研究概览

简要总结

This study aims to adapt the current Youth-Nominated Support Team (YST) manual used to treat suicide risk for people at clinical high risk for psychosis.

详细描述

Psychotic disorders are characterized by high rates of suicidal ideation and behavior, and the risk for suicide appears to be greatest during the earliest stages of psychosis. A recent meta-analysis showed that the majority of youth at clinical high-risk (CHR) for psychosis experience suicidal ideation, and that approximately one in five make at least one suicide attempt. There are, however, no suicide prevention interventions specifically tailored to the needs of transition-aged youth at CHR, and no current best practice guidelines for how to respond to suicide risk in this population. The Youth-Nominated Support Team (YST) intervention has recently been shown to reduce mortality among adolescents and is potentially highly adaptable within the context of existing CHR services. YST is intended as an adjunctive treatment and is primarily delivered towards support persons rather than the youth themselves, and therefore would not interfere or overlap with the already extensive direct services provided in CHR treatment settings. The proposed project intends to adapt the YST intervention for CHR populations. Specifically, the investigators aim to: (1) adapt YST for CHR based on stakeholder input (i.e., clients, family/friends, clinicians) and to develop a new treatment manual and submit an additional IRB to cover the next two aims -- (2) to implement YST in a single CHR clinic and to revise the intervention based on input from clients, providers, and support person and (3) conduct a pilot randomized clinical trial at four SAMHSA funded CHR sites to test the efficacy of the adapted YST intervention and to identify underlying mechanisms of change. The investigators hypothesize that the revised intervention will be superior to existing practice for the reduction of suicidal ideation and behavior.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
12 Years 至 25 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • A person with suicidal ideation in the past 3 months or suicidal attempt in the past year
  • A person who is receiving or has received treatment for psychosis risk symptoms
  • Between the ages of 12-25

排除标准

  • Cannot have participated in the first 2 phases of the study (focus groups and adaption of the YST-CHR manual)

研究组 & 干预措施

YST-CHR Group

Experimental

This group will recieve the new adapted YST treatment (YST-CHR). Clinicians will administer this treatment. Neither group will be blind.

干预措施: Youth-Nominated Support Teams for CHR (Behavioral)

Treatment as usual

No Intervention

This group will receive their usual therapy/treatment as usual.

结局指标

主要结局

Social Connectedness

时间窗: 3-months after intervention

Connectedness will be measured with the 5-item Thwarted Belongingness subscale of the Interpersonal Needs Questionnaire. Scores range from 15-105 and a higher score indicates lower social connectedness.

Increased Hope

时间窗: 3-months after intervention

Hopelessness will be measured with the 4-item Beck Hopelessness Scale (BHS). Hopelessness may be a very sensitive indicator of subsequent suicide risk, particularly among youth with psychosis. The total BHS score is a sum of item responses from 0 to 20 such that higher scores reflect higher levels of hopelessness. Scores greater than 14 identify severe hopelessness.

Treatment Engagement

时间窗: 3-months after intervention

This will be measured using clinic records of appointment attendance to determine number of therapy sessions attended.

次要结局

  • Severity and Intensity of Suicidal Ideation(baseline, 6 weeks after intervention, and 3 months after intervention)
  • Severity and Intensity of Suicidal Ideation(Baseline, 6 weeks after intervention, and 3 months after intervention)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Jason Eric Schiffman

Director of Clinical Training

University of California, Irvine

研究点 (1)

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