The effect of anti-inflammatory formula to reduce inflammation in intensive care unit patients

Not Applicable

• Conditions: multiple truama.; Injury, poisoning and certain other consequences of external causes; S00-T98

• Registration Number: IRCT20180515039674N1
• Lead Sponsor: Mashhad University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 15 June 2020

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

age between 18-65
Gastrointestinal tract with normal function and indications of Entral Nutrition
Diagnosis of moderate to severe trauma based on GCS (4-14)

Exclusion Criteria

failure to start enteral nutrition during the first 48 hours of admission
Any history of cardiovascular disease
Patients who are less than 96 hours in intensive care unit.
Patients who are predicted to die within 12 hours of admission to the intensive care unit.
Patients who are contraindicated for receiving enteral nutrition
Patient dissatisfaction or their legal guardian

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Tumor necrosis factor-a. Timepoint: at the baseline, 7 and 14 days after intervention. Method of measurement: Enzyme-linked immunosorbent assay.;Hs-CRP. Timepoint: at the baseline, 7 and 14 days after intervention. Method of measurement: Enzyme-linked immunosorbent assay.

Secondary Outcome Measures

Name	Time	Method
Alkaline phosphatase. Timepoint: At the baseline and 14 days after starting intervention. Method of measurement: Auto-analyzer.;Aspartate Aminotransferase. Timepoint: At the baseline and 14 days after starting intervention. Method of measurement: Auto-analyzer.;Alanine Aminotransferase. Timepoint: At the baseline and 14 days after starting intervention. Method of measurement: Auto-analyzer.;Blood Glucose. Timepoint: At the baseline and 14 days after starting intervention. Method of measurement: Auto-analyzer.;Triglyceride. Timepoint: At the baseline and 14 days after starting intervention. Method of measurement: Auto-analyzer.