Eggs as Part of a Healthy Breakfast

Not Applicable

Completed

• Conditions: Cardiovascular Diseases
• Interventions: Other: Eggs - 2 per day for breakfast; Other: 1 packet of oatmeal per day

• Registration Number: NCT02297464
• Lead Sponsor: University of Connecticut

Brief Summary

Contrary to popular belief, previous studies have demonstrated beneficial effects of whole egg consumption in modifying biomarkers indicative of a greater risk of coronary heart disease (CHD), chronic inflammation, and insulin resistance. The following study is designed to conduct a comprehensive evaluation of consuming an egg-based breakfast compared to an oatmeal-based breakfast on lipid biomarkers, oxidative stress, inflammation, insulin sensitivity, and satiety in young, healthy men and women. The investigators hypothesize that the consumption of 2 eggs per day will not negatively impact plasma lipids in a young, healthy population.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-07
• Study First Submitted: 2014-11-13
• Study First Submitted QC: 2014-11-20
• Study First Posted: 2014-11-21
• Primary Completion: 2014-12
• Status Verified: 2018-03
• Study Completion: 2018-03
• Last Update Submitted: 2018-03-21
• Last Update Posted: 2018-03-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• BMI 18.5-30, willing to consume eggs and oatmeal daily, proficient in English, and with a healthy lipid profile.

Exclusion Criteria

• Currently have liver disease, renal disease, diabetes, cancer, history of stroke or heart disease
• Currently taking glucose lowering drugs or supplements
• Plasma triglycerides >500 mg/dL, glucose >126, total cholesterol >240
• Pregnant, lactating, or have endocrine or metabolic disorders
• BMI ≥ 30
• Blood pressure > 140/90 (average of 3 readings)
• Allergies to eggs
• Celiac disease or gluten sensitivity

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Oatmeal - 1 packet per day for breakfast	1 packet of oatmeal per day	Participants will consume 1 packet of oatmeal per day for breakfast for 4 weeks of the study.
Eggs - 2 per day for breakfast	1 packet of oatmeal per day	Participants will consume 2 eggs per day for breakfast for 4 weeks of the study.
Eggs - 2 per day for breakfast	Eggs - 2 per day for breakfast	Participants will consume 2 eggs per day for breakfast for 4 weeks of the study.
Oatmeal - 1 packet per day for breakfast	Eggs - 2 per day for breakfast	Participants will consume 1 packet of oatmeal per day for breakfast for 4 weeks of the study.

Primary Outcome Measures

Name	Time	Method
Spectrophotometry, NMR and ELISA will assess plasma lipids.	1 year

Secondary Outcome Measures

Name	Time	Method
Visual analog scales (VAS) and ELISA assays will assess satiety.	1 year

Trial Locations

Locations (1)

University of Connecticut; 🇺🇸 Storrs, Connecticut, United States