Egg Consumption and Muscular Adaptations

Not Applicable

Completed

• Conditions: Hypertrophy
• Interventions: Dietary Supplement: Whole egg and resistance training; Dietary Supplement: Egg whites and resistance training

• Registration Number: NCT04381390
• Lead Sponsor: Alexei Wong

Brief Summary

Eggs may be a viable alternative to various types of supplemental proteins given its similar ratings on various measures of dietary protein quality.

The investigators hypothesis is that whole eggs would create a greater improvement in skeletal regulatory markers, hormonal responses and body composition than egg white ingestion in resistance-trained men.

Detailed Description

The aim of this investigation was to compare the effects of whole egg versus egg white ingestion (daily and after training sessions) during 12 weeks of resistance training on skeletal muscle regulatory markers, hormonal responses and body composition in resistance-trained men. Specific aims of the study are to:

To investigate the extent to which both whole egg and egg white ingestion will improve anabolic factors, fat free mass, fat mass and decrease catabolic markers after 12 weeks of resistance training in resistance-trained men.

Study Timeline

• Study Start: 2018-09-10
• Primary Completion: 2019-10-02
• Study Completion: 2019-10-02
• Status Verified: 2020-05
• Study First Submitted: 2020-05-01
• Study First Submitted QC: 2020-05-05
• Last Update Submitted: 2020-05-05
• Study First Posted: 2020-05-08
• Last Update Posted: 2020-05-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 30

Inclusion Criteria

• performing resistance training at least three times a week for 1 year prior to the start of the study
• not taking any dietary supplements or medications for at least 1 year prior to the start of the study
• no known medical issues
• no alcohol consumption or smoking for at least 1 year prior to the start of the study
• no egg allergy/sensitivity.

Exclusion Criteria

• non-willingness to continue nutritional or exercise protocols
• participation in exercise other than the prescribed resistance training program
• consumption of dietary supplement (other than egg) during the study period
• Missing more than one resistance training session or post-exercise egg consumption throughout the study period

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Whole egg consumption	Whole egg and resistance training	This arm involved whole egg consumption concomitant with 12 weeks of resistance training. Subject ingested three whole eggs per day immediately after resistance training.
Egg whites consumption	Egg whites and resistance training	This arm involved egg white consumption concomitant with 12 weeks of resistance training. Subject ingested an isonitrogenous quantity of six egg whites per day immediately after resistance training.

Primary Outcome Measures

Name	Time	Method
Circulatory hormone levels	12 weeks	Fasting blood samples were collected from the antecubital vein using standard procedures and then analized to establish concentrations of testosterone, IGF-1, insulin and cortisol
Muscle mass	12 weeks	Skeletal muscle mass will be evaluated using computed tomography
Circulatory Myokines levels	12 weeks	Fasting blood samples were collected from the antecubital vein using standard procedures and then analized to establish concentration of myostatin, follistatin, FGF-2, TGF-β1 and ACVA.
Body fatness	12 weeks	Body fat will be evaluated using bioelectrical impedance

Secondary Outcome Measures

Name	Time	Method
Muscular Strength	12 weeks	Using 1 repetition maximum

Trial Locations

Locations (1)

Marymount University; 🇺🇸 Arlington, Virginia, United States