Comparison of the results of treatment of the primary parathyroid adenoma with surgery or ablation with ethanol.

Phase 3

Recruiting

• Conditions: Benign parathyroid adenoma.; Benign neoplasm of parathyroid gland; D35.1

• Registration Number: IRCT20210204050241N1
• Lead Sponsor: Esfahan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 26 May 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

Patients with symptomatic benign parathyroid adenoma confirmed by ultrasound, MIBI scan, and fine needle aspiration

Exclusion Criteria

Patients with MEN1 or MEN2 syndrome
Patients with suspected parathyroid malignant adenoma
Patients with secondary or tertiary hyperparathyroidism
Not willing to participate in the trial
GFR<30 ml/min/1.72 m2
age above 50

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Serum calcium level. Timepoint: Before the intervention, 24 hours, two weeks, three months, and six months after the intervention. Method of measurement: Blood sample tests.;Serum PTH level. Timepoint: Before the intervention, 24 hours, two weeks, three months, and six months after the intervention. Method of measurement: Blood sample tests.

Secondary Outcome Measures

Name	Time	Method
Adenoma recurrence (reoperation or re-injection of alcohol). Timepoint: Within 3 months and 6 months after the intervention. Method of measurement: Changes in serum calcium and parathyroid hormone levels after intervention.