Normobaric Hypoxic Training and Multiple Sclerosis

Not Applicable

Completed

• Conditions: Multiple Sclerosis
• Interventions: Other: Normoxic training; Other: Hypoxic training

• Registration Number: NCT02509897
• Lead Sponsor: Charite University, Berlin, Germany

Brief Summary

To study the effects of normobaric hypoxic training on cardiorespiratory fitness, resting, postprandial and exercise activity energy expenditure, immunoregulatory functions and serum erythropoietin levels in relapsing-remitting multiple sclerosis patients.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-07
• Study First Submitted: 2015-07-24
• Study First Submitted QC: 2015-07-27
• Study First Posted: 2015-07-28
• Primary Completion: 2017-12
• Study Completion: 2018-07
• Status Verified: 2022-07
• Last Update Submitted: 2022-07-07
• Last Update Posted: 2022-07-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 39

Inclusion Criteria

• stable immunomodulatory therapy
• expanded disability status scale score < 4.5
• body mass index 18.5 - 29.9 kg/m2

Exclusion Criteria

• clinically relevant heart, lung, liver, and kidney diseases

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Normoxic training	Normoxic training	Endurance training
Hypoxic training	Hypoxic training	Endurance training

Primary Outcome Measures

Name	Time	Method
Activity energy expenditure measured by indirect calorimetry (respiratory chamber)	Change from baseline at 4 weeks

Trial Locations

Locations (1)

Experimental & Clinical Research Center; 🇩🇪 Berlin, Germany