NCT02509897已完成不适用
Cardiorespiratory, Metabolic and Immunoregulatory Response to Hypoxia in Multiple Sclerosis Patients: A Pilot Study
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 39
- 试验地点
- 1
- 主要终点
- Activity energy expenditure measured by indirect calorimetry (respiratory chamber)
研究概览
简要总结
To study the effects of normobaric hypoxic training on cardiorespiratory fitness, resting, postprandial and exercise activity energy expenditure, immunoregulatory functions and serum erythropoietin levels in relapsing-remitting multiple sclerosis patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 20 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •stable immunomodulatory therapy
- •expanded disability status scale score < 4.5
- •body mass index 18.5 - 29.9 kg/m2
排除标准
- •clinically relevant heart, lung, liver, and kidney diseases
研究组 & 干预措施
Hypoxic training
Active Comparator
Endurance training
干预措施: Hypoxic training (Other)
Normoxic training
Placebo Comparator
Endurance training
干预措施: Normoxic training (Other)
结局指标
主要结局
Activity energy expenditure measured by indirect calorimetry (respiratory chamber)
时间窗: Change from baseline at 4 weeks
次要结局
未报告次要终点
研究者
Anja Maehler
Principal Investigator
Charite University, Berlin, Germany
研究点 (1)
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