Trifluoperazine Effectiveness in Treatment of Coronavirus
- Conditions
- COVID-19.?????? ??? ?????J00-J99
- Registration Number
- IRCT20200329046892N1
- Lead Sponsor
- Rasht University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 70
?All of the patients admitted to Razi hospital of Rasht and diagnosed for COVID-19 in April-March 2020
18 years old and more
?Fever (oral temperature more than 37.8)
At least one of the following criteria
Respiratory rate 24 and more per minute
At rest SPO2 fewer than 94
PCR positive
Pulmonary involvement in CT or chest X-ray
Those who aren't willing to participate in the study based on personal satisfaction
concomitant use of an anti-psychotic drug
History of epileptic disorders
Parkinson's Disease
Dementia
Symptomatic hepatic dysfunction
Allergic reaction to Phenothiazines
History of pheochromocytoma
Any major drug-interaction between routine-taken drugs with trifluoperazine
Pregnancy and breastfeeding
Previous COVID-19 treatment
Multi-organ failure evidences
Need to mechanical ventilation on entrance to the study
eGFR< 50 mL/min
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method