Effect of administration of cefazolin in cesarean delivery on maternal postoperative infections and early neonatal complications
Phase 3
- Conditions
- Early neonatal complications (rash, diarrhea, oral candidiasis) and maternal infections after elective cesarean section.Antibiotics associated rash, diarrhea and oral candidiasis in neonate and maternal genitourinary and surgical site infectionsP83.9, P78
- Registration Number
- IRCT201506084339N10
- Lead Sponsor
- Vice chancellor of research, Bushehr University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 204
Inclusion Criteria
primi gravid; normal BMI
Exclusion criteria:
Obese women; history of antibiotic consumption in one week prior to cesarean section; immunosuppression; history of corticosteroid consumption; neonates with meconium stained amniotic fluid; duration of operation more than 30 minutes; patients with comorbidity.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Diarrhea, rash and oral candidiasis in neonate. Timepoint: During first 48 hours after delivery and one week postdelivery. Method of measurement: History and physical examination.
- Secondary Outcome Measures
Name Time Method Surgical site infection. Timepoint: During first 48 hours post delivery and one week post delivery. Method of measurement: History, physical examination.;Metritis. Timepoint: During first 48 hours post delivery and one week post delivery. Method of measurement: History, physical examination.;Urinary tract infection. Timepoint: During first 48 hours post delivery and one week post delivery. Method of measurement: History, physical examination, urinalysis and urine culture.;Breastfeeding satisfaction. Timepoint: During first 48 hours post delivery and one week post delivery. Method of measurement: History.