Effect of Naproxen in the treatment of cellulitis
Early Phase 1
- Conditions
- Cellulitis.Cellulitis and acute lymphangitis
- Registration Number
- IRCT20201204049598N1
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Hospitalized patients with a diagnosis of cellulitis
Age over 18 years
Willingness to participate in this clinical trial
Exclusion Criteria
Allergy to Penicillin, Cefazolin or Naproxen
Pregnant women
Immunodeficiency
Patients with mucocutaneous diseases
Patients with kidney diseases
Patients with vascular catheters
Patients suspected of having septic arthritis or osteomyelitis
Patients with infected diabetic foot ulcers
Bite or the presence of a foreign body in the wound
Perianal cellulitis
Injecting substance abuse
Hospitalization during the last three months
Chronic hemodialysis patients
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Erythema. Timepoint: Before the intervention, 2, 3, and 5 to 7 days after the start of the intervention. Method of measurement: Trained doctor report.;Warmth. Timepoint: Before the intervention, 2, 3, and 5 to 7 days after the start of the intervention. Method of measurement: Trained doctor report.;Tenderness. Timepoint: Before the intervention, 2, 3, and 5 to 7 days after the start of the intervention. Method of measurement: Trained doctor report.;Body temperature. Timepoint: Before the intervention, 2, 3, and 5 to 7 days after the start of the intervention. Method of measurement: Using a mercury thermometer.;Reduce exudate secretion from the wound. Timepoint: Before the intervention, 2, 3, and 5 to 7 days after the start of the intervention. Method of measurement: Trained doctor report.;Hospitalization duration. Timepoint: Before the intervention, 2, 3, and 5 to 7 days after the start of the intervention. Method of measurement: Medical record.
- Secondary Outcome Measures
Name Time Method Epigastric pain. Timepoint: Before the intervention, 2, 3, and 5 to 7 days after the start of the intervention. Method of measurement: Trained doctor report.;Diarreha. Timepoint: Before the intervention, 2, 3, and 5 to 7 days after the start of the intervention. Method of measurement: Trained doctor report.;Itching. Timepoint: Before the intervention, 2, 3, and 5 to 7 days after the start of the intervention. Method of measurement: Trained doctor report.;Skin rash. Timepoint: Before the intervention, 2, 3, and 5 to 7 days after the start of the intervention. Method of measurement: Trained doctor report.