The effect of Rosiglitazone in the treatment of depressio
Phase 2
- Conditions
- Major depressive disorder.Major depressive disorder, single episode
- Registration Number
- IRCT20090117001556N152
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Diagnosed with major depressive disorder (MDD) based on DSM5
Depression severity should be above 22 according to the Hamilton Depression Scale
Age between 18-60
Exclusion Criteria
Psychotic patients
Diagnosis of any disturbances in other axes
The use of psychoactive drugs
The use of antidepressants in the last one month or ECT in the last two months
History of cardiovascular disease (EKG can be taken, and if there is a problem in the function of heart, the patient is excluded from the study)
Thyroid problems
Pregnant and lactating women
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of depression. Timepoint: Weeks: 0-2-4-6. Method of measurement: by Hamiltion Depression Rating Scale.
- Secondary Outcome Measures
Name Time Method