The effect of Rosiglitazone on negative symptoms in schizophrenia
- Conditions
- Schizophrenia.Schizophrenia
- Registration Number
- IRCT20090117001556N159
- Lead Sponsor
- niversity of social welfare and rehabilitation sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 50
Diagnosis of schizophrenia based on DSM-5
Age between 18-50
At least 2 years have been passed since the diagnosis
Have been stable with risperidone treatment for at least 2 months
Normal ECG
Head trauma
History of shock therapy during the last three months
Neurosurgery
Diagnosis of acute or chronic systemic disease
Alcohol or drug addiction in the last 6 months
Suicidal ideation
Pregnancy or lactation
IQ less than 70 based on the diagnosis of a psychiatrist
ECT during recent two months
Taking oral antipsychotics, excluding risperidone, in the past week or long-acting antipsychotics in the past month
The presence of another diagnosis in axis II
History of heart disease
Family history of heart disease and heart failure
Taking insulin
Liver disorders
The development of a drug complication that requires emergency action: edema, congestive heart failure, heart pain and changes in the basic ECG, hypoglycemia, the occurrence of malignant neuroleptic syndrome
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method